Names & Taxonomy

Uniprot ID:
A8K6T3
Entry Name:
A8K6T3_HUMAN
Status:
unreviewed
Protein Names:
cDNA FLJ78674, highly similar to Homo sapiens desmocollin type 4
Organism:
Homo sapiens (Human)

Structure

Length:
896
Sequence:
MAAAGPRRSVRGAVCLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRSADLIRSSDPDFRVLNDGTVYTARAVALSDKKRSFTIWLSDKKKQTQKEVTVLLEHQKKVSKTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPHPLPIRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNITVLAIDKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAATKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGGQETIEMMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEKLHRCNQNEDRMPSQDYVLTYNYEGRGSPAGSVGCCSEKQEEDGLDFLNNLEPKFITLAEACTKR

Subcellular location

Subcellular Location:
Cell membrane

Function

Function:
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Gene Ontology Go:
integral component of membrane
plasma membrane
calcium ion binding
homophilic cell adhesion via plasma membrane adhesion molecules
Gene Ontology Biological Process:
homophilic cell adhesion via plasma membrane adhesion molecules
Gene Ontology Molecular Function:
calcium ion binding
Gene Ontology Cellular Component:
integral component of membrane
plasma membrane
Keywords:
Calcium
Cell adhesion
Cell membrane
Membrane
Repeat
Signal
Transmembrane
Transmembrane helix