Names & Taxonomy
- Uniprot ID:
- X5DQM5
- Entry Name:
- X5DQM5_HUMAN
- Status:
- unreviewed
- Protein Names:
- Adrenoceptor beta 2 surface isoform A (Fragment)
- Gene Names:
- ADRB2
- Gene Names Primary:
- ADRB2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 413
- Sequence:
- MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
Subcellular location
- Subcellular Location:
- Cell membrane
Function
- Gene Ontology Go:
- apical plasma membrane
axon
caveola
dendritic spine
endosome
integral component of membrane
neuronal cell body membrane
nucleus
sarcolemma
beta2-adrenergic receptor activity
dopamine binding
drug binding
epinephrine binding
norepinephrine binding
adenylate cyclase-activating G-protein coupled receptor signaling pathway
aging
associative learning
bone resorption
brown fat cell differentiation
cellular response to hypoxia
diaphragm contraction
diet induced thermogenesis
estrous cycle
excitatory postsynaptic potential
female pregnancy
heat generation
liver regeneration
negative regulation of angiogenesis
negative regulation of inflammatory response
negative regulation of multicellular organism growth
negative regulation of ossification
negative regulation of platelet aggregation
negative regulation of smooth muscle contraction
negative regulation of urine volume
positive regulation of apoptotic process
positive regulation of ATPase activity
positive regulation of bone mineralization
positive regulation of cell proliferation
positive regulation of potassium ion transport
positive regulation of skeletal muscle tissue growth
positive regulation of sodium ion transport
positive regulation of the force of heart contraction by epinephrine
positive regulation of transcription from RNA polymerase II promoter
positive regulation of vasodilation
regulation of calcium ion transport
regulation of sensory perception of pain
response to cold
response to dexamethasone
response to estrogen
response to monoamine
response to progesterone
response to testosterone
synaptic transmission, glutamatergic
vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
wound healing - Gene Ontology Biological Process:
- adenylate cyclase-activating G-protein coupled receptor signaling pathway
aging
associative learning
bone resorption
brown fat cell differentiation
cellular response to hypoxia
diaphragm contraction
diet induced thermogenesis
estrous cycle
excitatory postsynaptic potential
female pregnancy
heat generation
liver regeneration
negative regulation of angiogenesis
negative regulation of inflammatory response
negative regulation of multicellular organism growth
negative regulation of ossification
negative regulation of platelet aggregation
negative regulation of smooth muscle contraction
negative regulation of urine volume
positive regulation of apoptotic process
positive regulation of ATPase activity
positive regulation of bone mineralization
positive regulation of cell proliferation
positive regulation of potassium ion transport
positive regulation of skeletal muscle tissue growth
positive regulation of sodium ion transport
positive regulation of the force of heart contraction by epinephrine
positive regulation of transcription from RNA polymerase II promoter
positive regulation of vasodilation
regulation of calcium ion transport
regulation of sensory perception of pain
response to cold
response to dexamethasone
response to estrogen
response to monoamine
response to progesterone
response to testosterone
synaptic transmission, glutamatergic
vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
wound healing - Gene Ontology Molecular Function:
- beta2-adrenergic receptor activity
dopamine binding
drug binding
epinephrine binding
norepinephrine binding - Gene Ontology Cellular Component:
- apical plasma membrane
axon
caveola
dendritic spine
endosome
integral component of membrane
neuronal cell body membrane
nucleus
sarcolemma - Keywords:
- Cell membrane
G-protein coupled receptor
Membrane
Receptor
Transducer
Transmembrane
Transmembrane helix
Publication
- PubMed ID:
- 24722188