Names & Taxonomy
- Uniprot ID:
- U5Z977
- Entry Name:
- U5Z977_HUMAN
- Status:
- unreviewed
- Protein Names:
- NADH-ubiquinone oxidoreductase chain 6 (EC 1.6.5.3)
- Gene Names:
- ND6
- Gene Names Primary:
- ND6
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 174
- Sequence:
- MMYALFLLSVGLVMGFVGFSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYLGGMMVVFGYTTAMAIEEYPEAWGSGVEVLVSVLVGLAMEVGLVLWVKEYDGVVVVVNFNSVGSWMIYEGEGSGLIREDPIGAGALYDYGRWLVVVTGWTLFVGVYIVIEIARGN
Subcellular location
- Gene Encoded:
- Mitochondrion
Function
- Catalytic Activity:
- NADH + ubiquinone + 5 H(+)(In) = NAD(+) + ubiquinol + 4 H(+)(Out).
- Gene Ontology Go:
- integral component of membrane
mitochondrion
NADH dehydrogenase (ubiquinone) activity
response to cocaine
response to hydrogen peroxide
response to nicotine - Gene Ontology Biological Process:
- response to cocaine
response to hydrogen peroxide
response to nicotine - Gene Ontology Molecular Function:
- NADH dehydrogenase (ubiquinone) activity
- Gene Ontology Cellular Component:
- integral component of membrane
mitochondrion - Keywords:
- Membrane
Mitochondrion
NAD
Oxidoreductase
Transmembrane
Transmembrane helix
Publication
- PubMed ID:
- 24323467 24143169 24236171 24244704 24114781 24341918 25130626 24607387 24726474 25418795 24621318 25301575 24713204 25303789 25212860 24986921 24863938 25219341 25254093 25100861 25463651 25457022 25032828 25299580 24498190 24676463 24901532 25757516 25887241 25564040 26416320 26188410 25832481 26428318 25731774 25738654 25807545 26061688 26053380 26263179 26262956 26509580 26640946 26504230 25669617 25826227 26211407 26434580 26538459 25908660 26781090 26875094