Names & Taxonomy
- Uniprot ID:
- A0A024R2Z8
- Entry Name:
- A0A024R2Z8_HUMAN
- Status:
- unreviewed
- Protein Names:
- Parathyroid hormone receptor 1, isoform CRA_a
- Gene Names:
- PTHR1 hCG_14653
- Gene Names Orf:
- hCG_14653
- Gene Names Primary:
- PTHR1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 593
- Sequence:
- MGTARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPASIMESDKGWTSASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRVGLGLPLSPRLLPTATTNGHPQLPGHAKPGTPALETLETTPPAMAAPKDDGFLNGSCSGLDEEASGPERPPALLQEEWETVM
Function
- Gene Ontology Go:
- apical plasma membrane
basolateral plasma membrane
brush border membrane
cytosol
integral component of membrane
nucleus
receptor complex
parathyroid hormone receptor activity
peptide hormone binding
adenylate cyclase-activating G-protein coupled receptor signaling pathway
aging
bone mineralization
bone resorption
cell maturation
cell surface receptor signaling pathway
chondrocyte differentiation
negative regulation of cell proliferation
osteoblast development
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cell proliferation
positive regulation of cytosolic calcium ion concentration
positive regulation of inositol phosphate biosynthetic process - Gene Ontology Biological Process:
- adenylate cyclase-activating G-protein coupled receptor signaling pathway
aging
bone mineralization
bone resorption
cell maturation
cell surface receptor signaling pathway
chondrocyte differentiation
negative regulation of cell proliferation
osteoblast development
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cell proliferation
positive regulation of cytosolic calcium ion concentration
positive regulation of inositol phosphate biosynthetic process - Gene Ontology Molecular Function:
- parathyroid hormone receptor activity
peptide hormone binding - Gene Ontology Cellular Component:
- apical plasma membrane
basolateral plasma membrane
brush border membrane
cytosol
integral component of membrane
nucleus
receptor complex - Keywords:
- G-protein coupled receptor
Membrane
Receptor
Signal
Transducer
Transmembrane
Transmembrane helix
Publication
- PubMed ID:
- 11181995