Names & Taxonomy
- Uniprot ID:
- Q9Y4U1
- Entry Name:
- MMAC_HUMAN
- Status:
- reviewed
- Protein Names:
- Methylmalonic aciduria and homocystinuria type C protein
- Gene Names:
- MMACHC
- Gene Names Primary:
- MMACHC
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 282
- Sequence:
- MEPKVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGRVRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPDLPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQRLALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASPGP
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm
Function
- Function:
- May be involved in the binding and intracellular trafficking of cobalamin (vitamin B12).
- Pathway:
- Cofactor biosynthesis; adenosylcobalamin biosynthesis.
- Cross Reference Drug Bank:
- DB00115 DB00200
- Gene Ontology Go:
- cytosol
mitochondrion
cobalamin binding
cobalamin biosynthetic process
cobalamin metabolic process
small molecule metabolic process
vitamin metabolic process
water-soluble vitamin metabolic process - Gene Ontology Biological Process:
- cobalamin biosynthetic process
cobalamin metabolic process
small molecule metabolic process
vitamin metabolic process
water-soluble vitamin metabolic process - Gene Ontology Molecular Function:
- cobalamin binding
- Gene Ontology Cellular Component:
- cytosol
mitochondrion - Keywords:
- 3D-structure
Cobalamin
Cobalt
Complete proteome
Cytoplasm
Disease mutation
Phosphoprotein
Reference proteome - Interacts With:
- Q99707