Names & Taxonomy

Uniprot ID:
Q9Y277
Entry Name:
VDAC3_HUMAN
Status:
reviewed
Protein Names:
Voltage-dependent anion-selective channel protein 3 (VDAC-3) (hVDAC3) (Outer mitochondrial membrane protein porin 3)
Gene Names:
VDAC3
Gene Names Primary:
VDAC3
Organism:
Homo sapiens (Human)

Structure

Length:
283
Sequence:
MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLETKYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKRDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Mitochondrion outer membrane.

Function

Function:
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.
Cross Reference Drug Bank:
DB01375
Gene Ontology Go:
extracellular exosome
mitochondrial outer membrane
mitochondrion
nucleus
pore complex
nucleotide binding
porin activity
voltage-gated anion channel activity
adenine transport
regulation of anion transmembrane transport
regulation of cilium assembly
Gene Ontology Biological Process:
adenine transport
regulation of anion transmembrane transport
regulation of cilium assembly
Gene Ontology Molecular Function:
nucleotide binding
porin activity
voltage-gated anion channel activity
Gene Ontology Cellular Component:
extracellular exosome
mitochondrial outer membrane
mitochondrion
nucleus
pore complex
Keywords:
Acetylation
Alternative splicing
Complete proteome
Ion transport
Isopeptide bond
Membrane
Mitochondrion
Mitochondrion outer membrane
NAD
Nucleotide-binding
Phosphoprotein
Porin
Reference proteome
Transmembrane
Transmembrane beta strand
Transport
Ubl conjugation

Publication

PubMed ID:
9781040 9653160 15489334 10501981 10833333 19413330 19608861 21269460 25621951 25944712