Names & Taxonomy

Uniprot ID:
Q9UKG4
Entry Name:
S13A4_HUMAN
Status:
reviewed
Protein Names:
Solute carrier family 13 member 4 (Na(+)/sulfate cotransporter SUT-1) (NaS2)
Gene Names:
SLC13A4 SUT1
Gene Names Primary:
SLC13A4
Organism:
Homo sapiens (Human)

Structure

Length:
626
Sequence:
MGLLQGLLRVRKLLLVVCVPLLLLPLPVLHPSSEASCAYVLIVTAVYWVSEAVPLGAAALVPAFLYPFFGVLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLLLCFMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPISLDVKNSQPSLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQEKPQVLTPSPRKQKLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSLIFLEHFNNQYPAAEVVNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREQLSEKRIQEEYEKLGDISYPEMVTGFFFILMTVLWFTREPGFVPGWDSFFEKKGYRTDATVSVFLGFLLFLIPAKKPCFGKKNDGENQEHSLGTEPIITWKDFQKTMPWEIVILVGGGYALASGSKSSGLSTWIGNQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETLHINPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVIVMVAINTWGVSLFHLDTYPAWARVSNITDQA
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Membrane; Multi-pass membrane protein.

Function

Function:
Sodium/sulfate cotransporter that mediates sulfate reabsorption in the high endothelial venules (HEV).
Gene Ontology Go:
integral component of plasma membrane
plasma membrane
sodium:sulfate symporter activity
sodium ion transmembrane transport
sulfate transport
transmembrane transport
Gene Ontology Biological Process:
sodium ion transmembrane transport
sulfate transport
transmembrane transport
Gene Ontology Molecular Function:
sodium:sulfate symporter activity
Gene Ontology Cellular Component:
integral component of plasma membrane
plasma membrane
Keywords:
Complete proteome
Ion transport
Membrane
Polymorphism
Reference proteome
Sodium
Sodium transport
Symport
Transmembrane
Transmembrane helix
Transport

Publication

PubMed ID:
10535998 12853948 12690205 15489334 15607730