Names & Taxonomy
- Uniprot ID:
- Q9NY91
- Entry Name:
- SC5A4_HUMAN
- Status:
- reviewed
- Protein Names:
- Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3) (Solute carrier family 5 member 4)
- Gene Names:
- SLC5A4 SAAT1 SGLT2
- Gene Names Primary:
- SLC5A4
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 659
- Sequence:
- MASTVSPSTIAETPEPPPLSDHIRNAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCAYLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLAMGLIRMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLVTLGISLLTKPIPDVHLYRLCWVLRNSTEERIDIDAEEKSQEETDDGVEEDYPEKSRGCLKKAYDLFCGLQKGPKLTKEEEEALSKKLTDTSERPSWRTIVNINAILLLAVVVFIHGYYA
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane; Multi-pass membrane protein.
Function
- Function:
- Sodium-dependent glucose transporter.
- Gene Ontology Go:
- integral component of membrane
symporter activity
carbohydrate transport
sodium ion transport - Gene Ontology Biological Process:
- carbohydrate transport
sodium ion transport - Gene Ontology Molecular Function:
- symporter activity
- Gene Ontology Cellular Component:
- integral component of membrane
- Keywords:
- Complete proteome
Glycoprotein
Ion transport
Membrane
Polymorphism
Reference proteome
Sodium
Sodium transport
Sugar transport
Symport
Transmembrane
Transmembrane helix
Transport
Publication
- PubMed ID:
- 10591208