Names & Taxonomy
- Uniprot ID:
- Q9NW15
- Entry Name:
- ANO10_HUMAN
- Status:
- reviewed
- Protein Names:
- Anoctamin-10 (Transmembrane protein 16K)
- Gene Names:
- ANO10 TMEM16K
- Gene Names Primary:
- ANO10
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 660
- Sequence:
- MKVTLSALDTSESSFTPLVVIELAQDVKEETKEWLKNRIIAKKKDGGAQLLFRPLLNKYEQETLENQNLYLVGASKIRMLLGAEAVGLVKECNDNTMRAFTYRTRQNFKGFDDNNDDFLTMAECQFIIKHELENLRAKDEKMIPGYPQAKLYPGKSLLRRLLTSGIVIQVFPLHDSEALKKLEDTWYTRFALKYQPIDSIRGYFGETIALYFGFLEYFTFALIPMAVIGLPYYLFVWEDYDKYVIFASFNLIWSTVILELWKRGCANMTYRWGTLLMKRKFEEPRPGFHGVLGINSITGKEEPLYPSYKRQLRIYLVSLPFVCLCLYFSLYVMMIYFDMEVWALGLHENSGSEWTSVLLYVPSIIYAIVIEIMNRLYRYAAEFLTSWENHRLESAYQNHLILKVLVFNFLNCFASLFYIAFVLKDMKLLRQSLATLLITSQILNQIMESFLPYWLQRKHGVRVKRKVQALKADIDATLYEQVILEKEMGTYLGTFDDYLELFLQFGYVSLFSCVYPLAAAFAVLNNFTEVNSDALKMCRVFKRPFSEPSANIGVWQLAFETMSVISVVTNCALIGMSPQVNAVFPESKADLILIVVAVEHALLALKFILAFAIPDKPRHIQMKLARLEFESLEALKQQQMKLVTENLKEEPMESGKEKAT
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane
Function
- Function:
- Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1.
- Gene Ontology Go:
- integral component of membrane
intracellular
membrane
plasma membrane
calcium activated cation channel activity
intracellular calcium activated chloride channel activity
cation transmembrane transport
cation transport
chloride transmembrane transport
chloride transport
ion transmembrane transport
transmembrane transport - Gene Ontology Biological Process:
- cation transmembrane transport
cation transport
chloride transmembrane transport
chloride transport
ion transmembrane transport
transmembrane transport - Gene Ontology Molecular Function:
- calcium activated cation channel activity
intracellular calcium activated chloride channel activity - Gene Ontology Cellular Component:
- integral component of membrane
intracellular
membrane
plasma membrane - Keywords:
- Alternative splicing
Cell membrane
Complete proteome
Disease mutation
Membrane
Neurodegeneration
Polymorphism
Reference proteome
Transmembrane
Transmembrane helix