Names & Taxonomy
- Uniprot ID:
- Q9HB40
- Entry Name:
- RISC_HUMAN
- Status:
- reviewed
- Protein Names:
- Retinoid-inducible serine carboxypeptidase (EC 3.4.16.-) (Serine carboxypeptidase 1)
- Gene Names:
- SCPEP1 RISC SCP1 MSTP034 UNQ265/PRO302
- Gene Names Orf:
- MSTP034 UNQ265/PRO302
- Gene Names Primary:
- SCPEP1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 452
- Sequence:
- MELALRRSPVPRWLLLLPLLLGLNAGAVIDWPTEEGKEVWDYVTVRKDAYMFWWLYYATNSCKNFSELPLVMWLQGGPGGSSTGFGNFEEIGPLDSDLKPRKTTWLQAASLLFVDNPVGTGFSYVNGSGAYAKDLAMVASDMMVLLKTFFSCHKEFQTVPFYIFSESYGGKMAAGIGLELYKAIQRGTIKCNFAGVALGDSWISPVDSVLSWGPYLYSMSLLEDKGLAEVSKVAEQVLNAVNKGLYREATELWGKAEMIIEQNTDGVNFYNILTKSTPTSTMESSLEFTQSHLVCLCQRHVRHLQRDALSQLMNGPIRKKLKIIPEDQSWGGQATNVFVNMEEDFMKPVISIVDELLEAGINVTVYNGQLDLIVDTMGQEAWVRKLKWPELPKFSQLKWKALYSDPKSLETSAFVKSYKNLAFYWILKAGHMVPSDQGDMALKMMRLVTQQE
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted
Function
- Function:
- May be involved in vascular wall and kidney homeostasis.
- Active Site:
- ACT_SITE 167 167
- Gene Ontology Go:
- cytosol
extracellular exosome
serine-type carboxypeptidase activity
negative regulation of blood pressure
positive regulation of vasodilation
proteolysis involved in cellular protein catabolic process
retinoic acid metabolic process - Gene Ontology Biological Process:
- negative regulation of blood pressure
positive regulation of vasodilation
proteolysis involved in cellular protein catabolic process
retinoic acid metabolic process - Gene Ontology Molecular Function:
- serine-type carboxypeptidase activity
- Gene Ontology Cellular Component:
- cytosol
extracellular exosome - Keywords:
- Alternative splicing
Carboxypeptidase
Complete proteome
Direct protein sequencing
Glycoprotein
Hydrolase
Polymorphism
Protease
Reference proteome
Secreted
Signal