Names & Taxonomy
- Uniprot ID:
- Q9H7F0
- Entry Name:
- AT133_HUMAN
- Status:
- reviewed
- Protein Names:
- Probable cation-transporting ATPase 13A3 (EC 3.6.3.-) (ATPase family homolog up-regulated in senescence cells 1)
- Gene Names:
- ATP13A3 AFURS1
- Gene Names Primary:
- ATP13A3
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 1226
- Sequence:
- MDREERKTINQGQEDEMEIYGYNLSRWKLAIVSLGVICSGGFLLLLLYWMPEWRVKATCVRAAIKDCEVVLLRTTDEFKMWFCAKIRVLSLETYPVSSPKSMSNKLSNGHAVCLIENPTEENRHRISKYSQTESQQIRYFTHHSVKYFWNDTIHNFDFLKGLDEGVSCTSIYEKHSAGLTKGMHAYRKLLYGVNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAIVVMSIVSIVSSLYSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLNGTIMPCDAVLINGTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVAVAGIGFIYTIINSILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQRVENARFLSPEENVCNEMLVKSQFVACMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQLLPESTPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAGLCKPETVPVDFQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGGISLSELEASVASPFTSKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFSVTLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSVLSQIIICIGFQSLGFFWVKQQPWYEVWHPKSDACNTTGSGFWNSSHVDNETELDEHNIQNYENTTVFFISSFQYLIVAIAFSKGKPFRQPCYKNYFFVFSVIFLYIFILFIMLYPVASVDQVLQIVCVPYQWRVTMLIIVLVNAFVSITVEESVDRWGKCCLPWALGCRKKTPKAKYMYLAQELLVDPEWPPKPQTTTEAKALVKENGSCQIITIT
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane
Function
- Catalytic Activity:
- ATP + H(2)O = ADP + phosphate.
- Active Site:
- ACT_SITE 498 498 4-aspartylphosphate intermediate.
- Gene Ontology Go:
- integral component of plasma membrane
intracellular membrane-bounded organelle
membrane
ATP binding
cation-transporting ATPase activity
metal ion binding
cation transmembrane transport
cellular calcium ion homeostasis - Gene Ontology Biological Process:
- cation transmembrane transport
cellular calcium ion homeostasis - Gene Ontology Molecular Function:
- ATP binding
cation-transporting ATPase activity
metal ion binding - Gene Ontology Cellular Component:
- integral component of plasma membrane
intracellular membrane-bounded organelle
membrane - Keywords:
- ATP-binding
Alternative splicing
Complete proteome
Hydrolase
Magnesium
Membrane
Metal-binding
Nucleotide-binding
Phosphoprotein
Reference proteome
Transmembrane
Transmembrane helix