Names & Taxonomy
- Uniprot ID:
- Q9BY49
- Entry Name:
- PECR_HUMAN
- Status:
- reviewed
- Protein Names:
- Peroxisomal trans-2-enoyl-CoA reductase (TERP) (EC 1.3.1.38) (2,4-dienoyl-CoA reductase-related protein) (DCR-RP) (HPDHase) (Short chain dehydrogenase/reductase family 29C member 1) (pVI-ARL)
- Gene Names:
- PECR SDR29C1 PRO1004
- Gene Names Orf:
- PRO1004
- Gene Names Primary:
- PECR
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 303
- Sequence:
- MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKGAGDLSVVKKMKETFKEKAKL
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Peroxisome
Function
- Function:
- Participates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity.
- Pathway:
- Lipid metabolism; fatty acid biosynthesis.
- Catalytic Activity:
- Acyl-CoA + NADP(+) = trans-2,3-dehydroacyl-CoA + NADPH.
- Active Site:
- ACT_SITE 179 179 Proton acceptor.
- Cross Reference Drug Bank:
- DB00173
- Gene Ontology Go:
- intracellular membrane-bounded organelle
mitochondrion
peroxisomal membrane
peroxisome
receptor binding
trans-2-enoyl-CoA reductase (NADPH) activity
fatty acid biosynthetic process
oxidation-reduction process
phytol metabolic process - Gene Ontology Biological Process:
- fatty acid biosynthetic process
oxidation-reduction process
phytol metabolic process - Gene Ontology Molecular Function:
- receptor binding
trans-2-enoyl-CoA reductase (NADPH) activity - Gene Ontology Cellular Component:
- intracellular membrane-bounded organelle
mitochondrion
peroxisomal membrane
peroxisome - Keywords:
- 3D-structure
Alternative splicing
Complete proteome
Fatty acid biosynthesis
Fatty acid metabolism
Lipid biosynthesis
Lipid metabolism
NADP
Oxidoreductase
Peroxisome
Phosphoprotein
Polymorphism
Reference proteome