Names & Taxonomy
- Uniprot ID:
- Q9BQE3
- Entry Name:
- TBA1C_HUMAN
- Status:
- reviewed
- Protein Names:
- Tubulin alpha-1C chain (Alpha-tubulin 6) (Tubulin alpha-6 chain)
- Gene Names:
- TUBA1C TUBA6
- Gene Names Primary:
- TUBA1C
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 449
- Sequence:
- MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAVAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSADGEDEGEEY
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm, cytoskeleton.
Function
- Function:
- Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
- Gene Ontology Go:
- cytoplasm
microtubule
nucleus
vesicle
GTP binding
GTPase activity
structural constituent of cytoskeleton
structural molecule activity
'de novo' posttranslational protein folding
cell division
cellular protein metabolic process
cytoskeleton-dependent intracellular transport
microtubule-based process
protein folding - Gene Ontology Biological Process:
- 'de novo' posttranslational protein folding
cell division
cellular protein metabolic process
cytoskeleton-dependent intracellular transport
microtubule-based process
protein folding - Gene Ontology Molecular Function:
- GTPase activity
GTP binding
structural constituent of cytoskeleton
structural molecule activity - Gene Ontology Cellular Component:
- cytoplasm
microtubule
nucleus
vesicle - Keywords:
- Acetylation
Complete proteome
Cytoplasm
Cytoskeleton
Direct protein sequencing
GTP-binding
Microtubule
Nitration
Nucleotide-binding
Phosphoprotein
Reference proteome