Names & Taxonomy
- Uniprot ID:
- Q99679
- Entry Name:
- GPR21_HUMAN
- Status:
- reviewed
- Protein Names:
- Probable G-protein coupled receptor 21
- Gene Names:
- GPR21
- Gene Names Primary:
- GPR21
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 349
- Sequence:
- MNSTLDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLIISGNIIVIFVFHCAPLLNHHTTSYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEESLTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPLTYNTLVTPWRLRLCIFLIWLYSTLVFLPSFFHWGKPGYHGDVFQWCAESWHTDSYFTLFIVMMLYAPAALIVCFTYFNIFRICQQHTKDISERQARFSSQSGETGEVQACPDKRYAMVLFRITSVFYILWLPYIIYFLLESSTGHSNRFASFLTTWLAISNSFCNCVIYSLSNSVFQRGLKRLSGAMCTSCASQTTANDPYTVRSKGPLNGCHI
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane; Multi-pass membrane protein.
Function
- Function:
- Orphan receptor.
- Gene Ontology Go:
- integral component of plasma membrane
dopamine binding
dopamine neurotransmitter receptor activity, coupled via Gs
G-protein coupled receptor activity
adenylate cyclase-activating dopamine receptor signaling pathway
G-protein coupled receptor signaling pathway
glucose homeostasis
learning
negative regulation of insulin receptor signaling pathway
phospholipase C-activating dopamine receptor signaling pathway
positive regulation of multicellular organism growth
synaptic transmission, dopaminergic - Gene Ontology Biological Process:
- adenylate cyclase-activating dopamine receptor signaling pathway
glucose homeostasis
G-protein coupled receptor signaling pathway
learning
negative regulation of insulin receptor signaling pathway
phospholipase C-activating dopamine receptor signaling pathway
positive regulation of multicellular organism growth
synaptic transmission, dopaminergic - Gene Ontology Molecular Function:
- dopamine binding
dopamine neurotransmitter receptor activity, coupled via Gs
G-protein coupled receptor activity - Gene Ontology Cellular Component:
- integral component of plasma membrane
- Keywords:
- Cell membrane
Complete proteome
G-protein coupled receptor
Glycoprotein
Membrane
Receptor
Reference proteome
Transducer
Transmembrane
Transmembrane helix