Names & Taxonomy
- Uniprot ID:
- Q96AA3
- Entry Name:
- RFT1_HUMAN
- Status:
- reviewed
- Protein Names:
- Protein RFT1 homolog
- Gene Names:
- RFT1
- Gene Names Primary:
- RFT1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 541
- Sequence:
- MGSQEVLGHAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGVVNVRLTLLYSTTLFLAREAFRRACLSGGTQRDWSQTLNLLWLTVPLGVFWSLFLGWIWLQLLEVPDPNVVPHYATGVVLFGLSAVVELLGEPFWVLAQAHMFVKLKVIAESLSVILKSVLTAFLVLWLPHWGLYIFSLAQLFYTTVLVLCYVIYFTKLLGSPESTKLQTLPVSRITDLLPNITRNGAFINWKEAKLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLIFQPIEESFYIFFAKVLERGKDATLQKQEDVAVAAAVLESLLKLALLAGLTITVFGFAYSQLALDIYGGTMLSSGSGPVLLRSYCLYVLLLAINGVTECFTFAAMSKEEVDRYNFVMLALSSSFLVLSYLLTRWCGSVGFILANCFNMGIRITQSLCFIHRYYRRSPHRPLAGLHLSPVLLGTFALSGGVTAVSEVFLCCEQGWPARLAHIAVGAFCLGATLGTAFLTETKLIHFLRTQLGVPRRTDKMT
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane
Function
- Function:
- May be involved in N-linked oligosaccharide assembly. May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.
- Gene Ontology Go:
- endoplasmic reticulum membrane
integral component of membrane
lipid transporter activity
carbohydrate transport
cellular protein metabolic process
dolichol-linked oligosaccharide biosynthetic process
glycolipid translocation
post-translational protein modification
protein N-linked glycosylation via asparagine - Gene Ontology Biological Process:
- carbohydrate transport
cellular protein metabolic process
dolichol-linked oligosaccharide biosynthetic process
glycolipid translocation
post-translational protein modification
protein N-linked glycosylation via asparagine - Gene Ontology Molecular Function:
- lipid transporter activity
- Gene Ontology Cellular Component:
- endoplasmic reticulum membrane
integral component of membrane - Keywords:
- Complete proteome
Congenital disorder of glycosylation
Disease mutation
Membrane
Polymorphism
Reference proteome
Sugar transport
Transmembrane
Transmembrane helix
Transport