Names & Taxonomy

Uniprot ID:
Q969W1
Entry Name:
ZDH16_HUMAN
Status:
reviewed
Protein Names:
Probable palmitoyltransferase ZDHHC16 (EC 2.3.1.225) (Abl-philin 2) (Zinc finger DHHC domain-containing protein 16) (DHHC-16)
Gene Names:
ZDHHC16 APH2 UNQ2570/PRO6258
Gene Names Orf:
UNQ2570/PRO6258
Gene Names Primary:
ZDHHC16
Organism:
Homo sapiens (Human)

Structure

Length:
377
Sequence:
MRGQRSLLLGPARLCLRLLLLLGYRRRCPPLLRGLVQRWRYGKVCLRSLLYNSFGGSDTAVDAAFEPVYWLVDNVIRWFGVVFVVLVIVLTGSIVAIAYLCVLPLILRTYSVPRLCWHFFYSHWNLILIVFHYYQAITTPPGYPPQGRNDIATVSICKKCIYPKPARTHHCSICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSYGSWDLFREAYAAIEKMKQLDKNKLQAVANQTYHQTPPPTFSFRERMTHKSLVYLWFLCSSVALALGALTVWHAVLISRGETSIERHINKKERRRLQAKGRVFRNPYNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGNGMSWEPPPWVTAHSASVMAV
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Cytoplasm

Function

Function:
May be involved in apoptosis regulation.
Catalytic Activity:
Palmitoyl-CoA + -L-cysteine = -S-palmitoyl-L-cysteine + CoA.
Gene Ontology Go:
endoplasmic reticulum membrane
integral component of membrane
palmitoyltransferase activity
protein-cysteine S-palmitoyltransferase activity
zinc ion binding
apoptotic process
protein palmitoylation
Gene Ontology Biological Process:
apoptotic process
protein palmitoylation
Gene Ontology Molecular Function:
palmitoyltransferase activity
protein-cysteine S-palmitoyltransferase activity
zinc ion binding
Gene Ontology Cellular Component:
endoplasmic reticulum membrane
integral component of membrane
Keywords:
Acyltransferase
Alternative splicing
Apoptosis
Complete proteome
Cytoplasm
Endoplasmic reticulum
Membrane
Metal-binding
Reference proteome
Transferase
Transmembrane
Transmembrane helix
Zinc
Zinc-finger

Publication

PubMed ID:
17123647 12975309 15164054 15489334