Names & Taxonomy

Uniprot ID:
Q8TD20
Entry Name:
GTR12_HUMAN
Status:
reviewed
Protein Names:
Solute carrier family 2, facilitated glucose transporter member 12 (Glucose transporter type 12) (GLUT-12)
Gene Names:
SLC2A12 GLUT12 GLUT8
Gene Names Primary:
SLC2A12
Organism:
Homo sapiens (Human)

Structure

Length:
617
Sequence:
MVPVENTEGPSLLNQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALSDTTEELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSHHQEELVPKQPQKRKPQEQLLECNKLCGRGQSRQLSPET
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Endomembrane system

Function

Function:
Facilitative glucose transporter.
Gene Ontology Go:
endomembrane system
integral component of plasma membrane
perinuclear region of cytoplasm
plasma membrane
glucose transmembrane transporter activity
sugar:proton symporter activity
glucose import
glucose transmembrane transport
hexose transmembrane transport
proton transport
transmembrane transport
Gene Ontology Biological Process:
glucose import
glucose transmembrane transport
hexose transmembrane transport
proton transport
transmembrane transport
Gene Ontology Molecular Function:
glucose transmembrane transporter activity
sugar:proton symporter activity
Gene Ontology Cellular Component:
endomembrane system
integral component of plasma membrane
perinuclear region of cytoplasm
plasma membrane
Keywords:
Complete proteome
Cytoplasm
Glycoprotein
Membrane
Reference proteome
Sugar transport
Transmembrane
Transmembrane helix
Transport

Publication

PubMed ID:
11832379 14702039 14574404 15489334