Names & Taxonomy
- Uniprot ID:
- Q8TB96
- Entry Name:
- TIP_HUMAN
- Status:
- reviewed
- Protein Names:
- T-cell immunomodulatory protein (Protein TIP) (Integrin-alpha FG-GAP repeat-containing protein 1) (Linkin)
- Gene Names:
- ITFG1 LNKN-1 TIP CDA08
- Gene Names Orf:
- CDA08
- Gene Names Primary:
- ITFG1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 612
- Sequence:
- MAAAGRLPSSWALFSPLLAGLALLGVGPVPARALHNVTAELFGAEAWGTLAAFGDLNSDKQTDLFVLRERNDLIVFLADQNAPYFKPKVKVSFKNHSALITSVVPGDYDGDSQMDVLLTYLPKNYAKSELGAVIFWGQNQTLDPNNMTILNRTFQDEPLIMDFNGDLIPDIFGITNESNQPQILLGGNLSWHPALTTTSKMRIPHSHAFIDLTEDFTADLFLTTLNATTSTFQFEIWENLDGNFSVSTILEKPQNMMVVGQSAFADFDGDGHMDHLLPGCEDKNCQKSTIYLVRSGMKQWVPVLQDFSNKGTLWGFVPFVDEQQPTEIPIPITLHIGDYNMDGYPDALVILKNTSGSNQQAFLLENVPCNNASCEEARRMFKVYWELTDLNQIKDAMVATFFDIYEDGILDIVVLSKGYTKNDFAIHTLKNNFEADAYFVKVIVLSGLCSNDCPRKITPFGVNQPGPYIMYTTVDANGYLKNGSAGQLSQSAHLALQLPYNVLGLGRSANFLDHLYVGIPRPSGEKSIRKQEWTAIIPNSQLIVIPYPHNVPRSWSAKLYLTPSNIVLLTAIALIGVCVFILAIIGILHWQEKKADDREKRQEAHRFHFDAM
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted
Function
- Function:
- Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity).
- Gene Ontology Go:
- extracellular exosome
integral component of membrane - Gene Ontology Cellular Component:
- extracellular exosome
integral component of membrane - Keywords:
- Complete proteome
Glycoprotein
Membrane
Reference proteome
Secreted
Signal
Transmembrane
Transmembrane helix