Names & Taxonomy
- Uniprot ID:
- Q6ZSM3
- Entry Name:
- MOT12_HUMAN
- Status:
- reviewed
- Protein Names:
- Monocarboxylate transporter 12 (MCT 12) (Creatine transporter 2) (CRT2) (Solute carrier family 16 member 12)
- Gene Names:
- SLC16A12 MCT12
- Gene Names Primary:
- SLC16A12
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 486
- Sequence:
- MAKVNRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDHTTPEQNHVCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFARLIKRMRKTQLQFIAKESDPKLQLWTNGSVAYSVARELDQKHGEPVATAVPGYSLT
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane
Function
- Function:
- Proton-linked monocarboxylate transporter that mediates creatine transport across the plasma membrane.
- Gene Ontology Go:
- integral component of plasma membrane
creatine transmembrane transporter activity
lactate transmembrane transporter activity
symporter activity
creatine transmembrane transport
plasma membrane lactate transport - Gene Ontology Biological Process:
- creatine transmembrane transport
plasma membrane lactate transport - Gene Ontology Molecular Function:
- creatine transmembrane transporter activity
lactate transmembrane transporter activity
symporter activity - Gene Ontology Cellular Component:
- integral component of plasma membrane
- Keywords:
- Cataract
Cell membrane
Complete proteome
Membrane
Polymorphism
Reference proteome
Symport
Transmembrane
Transmembrane helix
Transport