Names & Taxonomy
- Uniprot ID:
- Q6UXG2
- Entry Name:
- K1324_HUMAN
- Status:
- reviewed
- Protein Names:
- UPF0577 protein KIAA1324 (Estrogen-induced gene 121 protein)
- Gene Names:
- KIAA1324 EIG121 UNQ2426/PRO4985
- Gene Names Orf:
- UNQ2426/PRO4985
- Gene Names Primary:
- KIAA1324
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 1013
- Sequence:
- MAEPGHSHHLSARVRGRTERRIPRLWRLLLWAGTAFQVTQGTGPELHACKESEYHYEYTACDSTGSRWRVAVPHTPGLCTSLPDPIKGTECSFSCNAGEFLDMKDQSCKPCAEGRYSLGTGIRFDEWDELPHGFASLSANMELDDSAAESTGNCTSSKWVPRGDYIASNTDECTATLMYAVNLKQSGTVNFEYYYPDSSIIFEFFVQNDQCQPNADDSRWMKTTEKGWEFHSVELNRGNNVLYWRTTAFSVWTKVPKPVLVRNIAITGVAYTSECFPCKPGTYADKQGSSFCKLCPANSYSNKGETSCHQCDPDKYSEKGSSSCNVRPACTDKDYFYTHTACDANGETQLMYKWAKPKICSEDLEGAVKLPASGVKTHCPPCNPGFFKTNNSTCQPCPYGSYSNGSDCTRCPAGTEPAVGFEYKWWNTLPTNMETTVLSGINFEYKGMTGWEVAGDHIYTAAGASDNDFMILTLVVPGFRPPQSVMADTENKEVARITFVFETLCSVNCELYFMVGVNSRTNTPVETWKGSKGKQSYTYIIEENTTTSFTWAFQRTTFHEASRKYTNDVAKIYSINVTNVMNGVASYCRPCALEASDVGSSCTSCPAGYYIDRDSGTCHSCPTNTILKAHQPYGVQACVPCGPGTKNNKIHSLCYNDCTFSRNTPTRTFNYNFSALANTVTLAGGPSFTSKGLKYFHHFTLSLCGNQGRKMSVCTDNVTDLRIPEGESGFSKSITAYVCQAVIIPPEVTGYKAGVSSQPVSLADRLIGVTTDMTLDGITSPAELFHLESLGIPDVIFFYRSNDVTQSCSSGRSTTIRVRCSPQKTVPGSLLLPGTCSDGTCDGCNFHFLWESAAACPLCSVADYHAIVSSCVAGIQKTTYVWREPKLCSGGISLPEQRVTICKTIDFWLKVGISAGTCTAILLTVLTCYFWKKNQKLEYKYSKLVMNATLKDCDLPAADSCAIMEGEDVEDDLIFTSKKSLFGKIKSFTSKRTPDGFDSVPLKTSSGGLDMDL
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane
Function
- Function:
- May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway.
- Gene Ontology Go:
- extracellular exosome
Golgi apparatus
integral component of plasma membrane
late endosome membrane
lysosomal membrane
poly(A) RNA binding
autophagosome assembly
cellular response to starvation
positive regulation of autophagosome assembly
positive regulation of vacuole organization - Gene Ontology Biological Process:
- autophagosome assembly
cellular response to starvation
positive regulation of autophagosome assembly
positive regulation of vacuole organization - Gene Ontology Molecular Function:
- poly(A) RNA binding
- Gene Ontology Cellular Component:
- extracellular exosome
Golgi apparatus
integral component of plasma membrane
late endosome membrane
lysosomal membrane - Keywords:
- Alternative splicing
Autophagy
Cell membrane
Complete proteome
Disulfide bond
Endosome
Glycoprotein
Golgi apparatus
Lysosome
Membrane
Polymorphism
Reference proteome
Signal
Transmembrane
Transmembrane helix