Names & Taxonomy

Uniprot ID:
Q6L8H4
Entry Name:
KRA51_HUMAN
Status:
reviewed
Protein Names:
Keratin-associated protein 5-1 (Keratin, cuticle, ultrahigh sulphur 1-like) (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1)
Gene Names:
KRTAP5-1 KAP5.1 KRN1L KRTAP5.1
Gene Names Primary:
KRTAP5-1
Organism:
Homo sapiens (Human)

Structure

Length:
278
Sequence:
MGCCGCSGGCGSSCGGCGSGCGGCGSGCGGCGSGCGGSGSSCCVPVCCCKPVCCRVPTCSCSSCGKGGCGSSGGSKGGCGSCGGCKGGCGSCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSGCGGCGSSCCVPVCCCKPMCCCVPACSCSSCGKGGCGSCGCSKGACGSCGGSKGGCGSCGGCKGGCGSCGGSKGGCGSGCGGCGSGCGVPVCCCSCSSCGSCAGSKGGCGSSCSQCSCCKPCCCSSGCGSSCCQSSCCKPCCSQSSCCVPVCCQCKI
Proteomes:
UP000005640

Function

Function:
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Gene Ontology Go:
keratin filament
Gene Ontology Cellular Component:
keratin filament
Keywords:
Complete proteome
Keratin
Reference proteome
Repeat

Publication

PubMed ID:
15144888