Names & Taxonomy
- Uniprot ID:
- Q6L8H4
- Entry Name:
- KRA51_HUMAN
- Status:
- reviewed
- Protein Names:
- Keratin-associated protein 5-1 (Keratin, cuticle, ultrahigh sulphur 1-like) (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1)
- Gene Names:
- KRTAP5-1 KAP5.1 KRN1L KRTAP5.1
- Gene Names Primary:
- KRTAP5-1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 278
- Sequence:
- MGCCGCSGGCGSSCGGCGSGCGGCGSGCGGCGSGCGGSGSSCCVPVCCCKPVCCRVPTCSCSSCGKGGCGSSGGSKGGCGSCGGCKGGCGSCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSGCGGCGSSCCVPVCCCKPMCCCVPACSCSSCGKGGCGSCGCSKGACGSCGGSKGGCGSCGGCKGGCGSCGGSKGGCGSGCGGCGSGCGVPVCCCSCSSCGSCAGSKGGCGSSCSQCSCCKPCCCSSGCGSSCCQSSCCKPCCSQSSCCVPVCCQCKI
- Proteomes:
- UP000005640
Function
- Function:
- In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
- Gene Ontology Go:
- keratin filament
- Gene Ontology Cellular Component:
- keratin filament
- Keywords:
- Complete proteome
Keratin
Reference proteome
Repeat
Publication
- PubMed ID:
- 15144888