Names & Taxonomy

Uniprot ID:
A0A0A0YLX2
Entry Name:
A0A0A0YLX2_HUMAN
Status:
unreviewed
Protein Names:
DNA polymerase (EC 2.7.7.7)
Gene Names:
U38
Gene Names Primary:
U38
Organism:
Homo sapiens (Human)

Structure

Length:
1012
Sequence:
MDSVSFFNPYLEANRLKKKSRSSYIRILPRGIMHDGAAGLIKDVCDSEPRMFYRDRQYLLSKEMTWPSLDIARSKDYDHMRMKFHIYDAVETLMFTDSIENLPFQYRHFVIPSGTVIRMFGRTEDGEKICVNVFGQEQYFYCECVDGKSLKATINNLMLTGEVKMSCSFVIEPADKLSLYGYNANTVVNLFKVSFGNFYVSQRIGKILQNEGFVVYEIDVDVLTRFFVDNGFLSFGWYNVKKYIPQDMGKGSNLEVEINCHVSDLVSLEDVNWPLYGCWSFDIECLGQNGNFPDAENLGDIVIQISVISFDTEGDRDERHLFTLGTCEKIDGVHIYEFASEFELLLGFFIFLRIESPEFITGYNINNFDLKYLCIRMDKIYHYDIGCFSKLKNGKIGISVPHEQYRKGFLQAQTKVFTSGVLYLDMYPVYSSKITAQNYKLDTIAKICLQQEKEQLSYKEIPKKFISGPSGRAVVGKYCLQDSVLVVRLFKQINYHYEVVEVARLAHVTARCVVFEGQQKKIFPCILTEAKRRNMILPSMVSSHNRQGIGYKGATVLEPKTGYYAVPTVVFDFQSLYPSIMMAHNLCYSTLVLDERQIAGLSESDILTVKLGDETHRFVKPCIRESVLGSLLKDWLAKRREVKAEMQNCSDPMMKLLLDKKQLALKTTCNSVYGVTGAAHGLLPCVAIAASVTCLGREMLCSTVDYVNSKMQSEQFFCEEFGLTSSDFTGDLKVEVIYGDTDSIFMSVRNMVNQSLRRIAPMIAKHITDRLFKSPIKLEFEKILCPLILICKKRYIGRQDDSLLIFKGVDLVRKTSCDFVKGVVKDIVDLLFFDEEVQTAAVEFSHMTQTQLREQGVPVGIHKILRRLCEAREELFQNRADVRHLMLSSVLSKEMAAYKQPNLAHLSVIRRLAQRKEEIPNVGDRIMYVLIAPSIGNKQTHNYELAEDPNYVIEHKIPIHAEKYFDQIIKAVTNAISPIFPKTDIKKEKLLLYLLPMKVYLDETFSAIAEVM

Function

Catalytic Activity:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
Gene Ontology Go:
3'-5' exonuclease activity
DNA binding
DNA-directed DNA polymerase activity
nucleotide binding
DNA replication
Gene Ontology Biological Process:
DNA replication
Gene Ontology Molecular Function:
3'-5' exonuclease activity
DNA binding
DNA-directed DNA polymerase activity
nucleotide binding
Keywords:
DNA replication
DNA-binding
DNA-directed DNA polymerase
Nucleotidyltransferase
Transferase

Publication

PubMed ID:
25355130 26784220