Names & Taxonomy

Uniprot ID:
Q4KMG0
Entry Name:
CDON_HUMAN
Status:
reviewed
Protein Names:
Cell adhesion molecule-related/down-regulated by oncogenes
Gene Names:
CDON CDO
Gene Names Primary:
CDON
Organism:
Homo sapiens (Human)

Structure

Length:
1287
Sequence:
MHPDLGPLCTLLYVTLTILCSSVSSDLAPYFTSEPLSAVQKLGGPVVLHCSAQPVTTRISWLHNGKTLDGNLEHVKIHQGTLTILSLNSSLLGYYQCLANNSIGAIVSGPATVSVAVLGDFGSSTKHVITAEEKSAGFIGCRVPESNPKAEVRYKIRGKWLEHSTENYLILPSGNLQILNVSLEDKGSYKCAAYNPVTHQLKVEPIGRKLLVSRPSSDDVHILHPTHSQALAVLSRSPVTLECVVSGVPAPQVYWLKDGQDIAPGSNWRRLYSHLATDSVDPADSGNYSCMAGNKSGDVKYVTYMVNVLEHASISKGLQDQIVSLGATVHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAGNGLKISGVTVEDVGMYQCVADNGIGFMHSTGRLEIENDGGFKPVIITAPVSAKVADGDFVTLSCNASGLPVPVIRWYDSHGLITSHPSQVLRSKSRKSQLSRPEGLNLEPVYFVLSQAGASSLHIQAVTQEHAGKYICEAANEHGTTQAEASLMVVPFETNTKAETVTLPDAAQNDDRSKRDGSETGLLSSFPVKVHPSAVESAPEKNASGISVPDAPIILSPPQTHTPDTYNLVWRAGKDGGLPINAYFVKYRKLDDGVGMLGSWHTVRVPGSENELHLAELEPSSLYEVLMVARSAAGEGQPAMLTFRTSKEKTASSKNTQASSPPVGIPKYPVVSEAANNNFGVVLTDSSRHSGVPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDIPPSKLSVEVRSLEPGSTYKFRVIAINHYGESFRSSASRPYQVVGFPNRFSSRPITGPHIAYTEAVSDTQIMLKWTYIPSSNNNTPIQGFYIYYRPTDSDNDSDYKRDVVEGSKQWHMIGHLQPETSYDIKMQCFNEGGESEFSNVMICETKVKRVPGASEYPVKDLSTPPNSLGSGGNVGPATSPARSSDMLYLIVGCVLGVMVLILMVFIAMCLWKNRQQNTIQKYDPPGYLYQGSDMNGQMVDYTTLSGASQINGNVHGGFLTNGGLSSGYSHLHHKVPNAVNGIVNGSLNGGLYSGHSNSLTRTHVDFEHPHHLVNGGGMYTAVPQIDPLECVNCRNCRNNNRCFTKTNSTFSSSPPPVVPVVAPYPQDGLEMKPLSHVKVPVCLTSAVPDCGQLPEESVKDNVEPVPTQRTCCQDIVNDVSSDGSEDPAEFSRGQEGMINLRIPDHLQLAKSCVWEGDSCAHSETEINIVSWNALILPPVPEGCAEKTMWSPPGIPLDSPTEVLQQPRET
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Cell membrane

Function

Function:
Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells (By similarity).
Gene Ontology Go:
cell surface
integral component of plasma membrane
plasma membrane
anterior/posterior pattern specification
cell adhesion
cell fate specification
cerebral cortex development
embryonic body morphogenesis
embryonic retina morphogenesis in camera-type eye
lens development in camera-type eye
muscle cell differentiation
myoblast fusion
positive regulation of MAPK cascade
positive regulation of muscle cell differentiation
positive regulation of myoblast differentiation
positive regulation of neural precursor cell proliferation
positive regulation of neuron differentiation
positive regulation of skeletal muscle tissue development
positive regulation of small GTPase mediated signal transduction
positive regulation of transcription from RNA polymerase II promoter
regulation of protein heterodimerization activity
skeletal muscle satellite cell differentiation
smoothened signaling pathway
Gene Ontology Biological Process:
anterior/posterior pattern specification
cell adhesion
cell fate specification
cerebral cortex development
embryonic body morphogenesis
embryonic retina morphogenesis in camera-type eye
lens development in camera-type eye
muscle cell differentiation
myoblast fusion
positive regulation of MAPK cascade
positive regulation of muscle cell differentiation
positive regulation of myoblast differentiation
positive regulation of neural precursor cell proliferation
positive regulation of neuron differentiation
positive regulation of skeletal muscle tissue development
positive regulation of small GTPase mediated signal transduction
positive regulation of transcription from RNA polymerase II promoter
regulation of protein heterodimerization activity
skeletal muscle satellite cell differentiation
smoothened signaling pathway
Gene Ontology Cellular Component:
cell surface
integral component of plasma membrane
plasma membrane
Keywords:
3D-structure
Alternative splicing
Cell membrane
Complete proteome
Disease mutation
Disulfide bond
Glycoprotein
Holoprosencephaly
Immunoglobulin domain
Membrane
Polymorphism
Reference proteome
Repeat
Signal
Transmembrane
Transmembrane helix
Interacts With:
P00519

Publication

PubMed ID:
9214393 16554811 15489334 18794898 20519495 21802063