Names & Taxonomy
- Uniprot ID:
- Q4KMG0
- Entry Name:
- CDON_HUMAN
- Status:
- reviewed
- Protein Names:
- Cell adhesion molecule-related/down-regulated by oncogenes
- Gene Names:
- CDON CDO
- Gene Names Primary:
- CDON
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 1287
- Sequence:
- MHPDLGPLCTLLYVTLTILCSSVSSDLAPYFTSEPLSAVQKLGGPVVLHCSAQPVTTRISWLHNGKTLDGNLEHVKIHQGTLTILSLNSSLLGYYQCLANNSIGAIVSGPATVSVAVLGDFGSSTKHVITAEEKSAGFIGCRVPESNPKAEVRYKIRGKWLEHSTENYLILPSGNLQILNVSLEDKGSYKCAAYNPVTHQLKVEPIGRKLLVSRPSSDDVHILHPTHSQALAVLSRSPVTLECVVSGVPAPQVYWLKDGQDIAPGSNWRRLYSHLATDSVDPADSGNYSCMAGNKSGDVKYVTYMVNVLEHASISKGLQDQIVSLGATVHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAGNGLKISGVTVEDVGMYQCVADNGIGFMHSTGRLEIENDGGFKPVIITAPVSAKVADGDFVTLSCNASGLPVPVIRWYDSHGLITSHPSQVLRSKSRKSQLSRPEGLNLEPVYFVLSQAGASSLHIQAVTQEHAGKYICEAANEHGTTQAEASLMVVPFETNTKAETVTLPDAAQNDDRSKRDGSETGLLSSFPVKVHPSAVESAPEKNASGISVPDAPIILSPPQTHTPDTYNLVWRAGKDGGLPINAYFVKYRKLDDGVGMLGSWHTVRVPGSENELHLAELEPSSLYEVLMVARSAAGEGQPAMLTFRTSKEKTASSKNTQASSPPVGIPKYPVVSEAANNNFGVVLTDSSRHSGVPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDIPPSKLSVEVRSLEPGSTYKFRVIAINHYGESFRSSASRPYQVVGFPNRFSSRPITGPHIAYTEAVSDTQIMLKWTYIPSSNNNTPIQGFYIYYRPTDSDNDSDYKRDVVEGSKQWHMIGHLQPETSYDIKMQCFNEGGESEFSNVMICETKVKRVPGASEYPVKDLSTPPNSLGSGGNVGPATSPARSSDMLYLIVGCVLGVMVLILMVFIAMCLWKNRQQNTIQKYDPPGYLYQGSDMNGQMVDYTTLSGASQINGNVHGGFLTNGGLSSGYSHLHHKVPNAVNGIVNGSLNGGLYSGHSNSLTRTHVDFEHPHHLVNGGGMYTAVPQIDPLECVNCRNCRNNNRCFTKTNSTFSSSPPPVVPVVAPYPQDGLEMKPLSHVKVPVCLTSAVPDCGQLPEESVKDNVEPVPTQRTCCQDIVNDVSSDGSEDPAEFSRGQEGMINLRIPDHLQLAKSCVWEGDSCAHSETEINIVSWNALILPPVPEGCAEKTMWSPPGIPLDSPTEVLQQPRET
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane
Function
- Function:
- Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells (By similarity).
- Gene Ontology Go:
- cell surface
integral component of plasma membrane
plasma membrane
anterior/posterior pattern specification
cell adhesion
cell fate specification
cerebral cortex development
embryonic body morphogenesis
embryonic retina morphogenesis in camera-type eye
lens development in camera-type eye
muscle cell differentiation
myoblast fusion
positive regulation of MAPK cascade
positive regulation of muscle cell differentiation
positive regulation of myoblast differentiation
positive regulation of neural precursor cell proliferation
positive regulation of neuron differentiation
positive regulation of skeletal muscle tissue development
positive regulation of small GTPase mediated signal transduction
positive regulation of transcription from RNA polymerase II promoter
regulation of protein heterodimerization activity
skeletal muscle satellite cell differentiation
smoothened signaling pathway - Gene Ontology Biological Process:
- anterior/posterior pattern specification
cell adhesion
cell fate specification
cerebral cortex development
embryonic body morphogenesis
embryonic retina morphogenesis in camera-type eye
lens development in camera-type eye
muscle cell differentiation
myoblast fusion
positive regulation of MAPK cascade
positive regulation of muscle cell differentiation
positive regulation of myoblast differentiation
positive regulation of neural precursor cell proliferation
positive regulation of neuron differentiation
positive regulation of skeletal muscle tissue development
positive regulation of small GTPase mediated signal transduction
positive regulation of transcription from RNA polymerase II promoter
regulation of protein heterodimerization activity
skeletal muscle satellite cell differentiation
smoothened signaling pathway - Gene Ontology Cellular Component:
- cell surface
integral component of plasma membrane
plasma membrane - Keywords:
- 3D-structure
Alternative splicing
Cell membrane
Complete proteome
Disease mutation
Disulfide bond
Glycoprotein
Holoprosencephaly
Immunoglobulin domain
Membrane
Polymorphism
Reference proteome
Repeat
Signal
Transmembrane
Transmembrane helix - Interacts With:
- P00519