Names & Taxonomy

Uniprot ID:
Q3LI67
Entry Name:
KRA63_HUMAN
Status:
reviewed
Protein Names:
Keratin-associated protein 6-3
Gene Names:
KRTAP6-3 KAP6.3
Gene Names Primary:
KRTAP6-3
Organism:
Homo sapiens (Human)

Structure

Length:
103
Sequence:
MCGSYYRNYNGGHGYGCCGYGGLGCGYGGCGYGCCGYGGLGFGYGGLDCGYGGLGCGYGSFCGCGYRGLDCGYGCGYGYVSHSFCGCGYRCGSGYGSSFGYYY
Proteomes:
UP000005640

Function

Function:
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Gene Ontology Go:
intermediate filament
Gene Ontology Cellular Component:
intermediate filament
Keywords:
Complete proteome
Keratin
Polymorphism
Reference proteome
Repeat

Publication

PubMed ID:
15489334