Names & Taxonomy
- Uniprot ID:
- Q2TU84
- Entry Name:
- Q2TU84_HUMAN
- Status:
- unreviewed
- Protein Names:
- Aspartate aminotransferase (EC 2.6.1.1)
- Gene Names:
- GIG18
- Gene Names Primary:
- GIG18
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 413
- Sequence:
- MAPPSVFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQKIANDNSLNHEYLPILGLAEFRSCASRLALEDDSPALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNTPVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIVVLHACAHNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFFCAQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRILTMRSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAVTKIQ
Function
- Catalytic Activity:
- L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
- Cofactor:
- COFACTOR: Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
- Cross Reference Drug Bank:
- DB00128
- Gene Ontology Go:
- L-aspartate:2-oxoglutarate aminotransferase activity
L-phenylalanine:2-oxoglutarate aminotransferase activity
pyridoxal phosphate binding
biosynthetic process
cellular amino acid metabolic process - Gene Ontology Biological Process:
- biosynthetic process
cellular amino acid metabolic process - Gene Ontology Molecular Function:
- L-aspartate:2-oxoglutarate aminotransferase activity
L-phenylalanine:2-oxoglutarate aminotransferase activity
pyridoxal phosphate binding - Keywords:
- Aminotransferase
Pyridoxal phosphate
Transferase