Names & Taxonomy
- Uniprot ID:
- Q15391
- Entry Name:
- P2Y14_HUMAN
- Status:
- reviewed
- Protein Names:
- P2Y purinoceptor 14 (P2Y14) (G-protein coupled receptor 105) (UDP-glucose receptor)
- Gene Names:
- P2RY14 GPR105 KIAA0001
- Gene Names Primary:
- P2RY14
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 338
- Sequence:
- MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane; Multi-pass membrane protein.
Function
- Function:
- Receptor for UDP-glucose and other UDP-sugar coupled to G-proteins. Not activated by ATP, ADP, UTP or ATP.
- Gene Ontology Go:
- integral component of membrane
integral component of plasma membrane
plasma membrane
G-protein coupled purinergic nucleotide receptor activity
UDP-activated nucleotide receptor activity
G-protein coupled purinergic nucleotide receptor signaling pathway
G-protein coupled receptor signaling pathway
immune response - Gene Ontology Biological Process:
- G-protein coupled purinergic nucleotide receptor signaling pathway
G-protein coupled receptor signaling pathway
immune response - Gene Ontology Molecular Function:
- G-protein coupled purinergic nucleotide receptor activity
UDP-activated nucleotide receptor activity - Gene Ontology Cellular Component:
- integral component of membrane
integral component of plasma membrane
plasma membrane - Keywords:
- 3D-structure
Cell membrane
Complete proteome
Disulfide bond
G-protein coupled receptor
Glycoprotein
Membrane
Polymorphism
Receptor
Reference proteome
Transducer
Transmembrane
Transmembrane helix