Names & Taxonomy

Uniprot ID:
Q14541
Entry Name:
HNF4G_HUMAN
Status:
reviewed
Protein Names:
Hepatocyte nuclear factor 4-gamma (HNF-4-gamma) (Nuclear receptor subfamily 2 group A member 2)
Gene Names:
HNF4G NR2A2
Gene Names Primary:
HNF4G
Organism:
Homo sapiens (Human)

Structure

Length:
408
Sequence:
MNTTDNGVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEVEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGASNDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSGQEQYKIAANQASVISHQHLSKQKQL
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Nucleus

Function

Function:
Transcription factor. Has a lower transcription activation potential than HNF4-alpha.
Gene Ontology Go:
nucleoplasm
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
sequence-specific DNA binding
steroid hormone receptor activity
transcription factor activity, sequence-specific DNA binding
zinc ion binding
endocrine pancreas development
gene expression
regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
Gene Ontology Biological Process:
endocrine pancreas development
gene expression
regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
Gene Ontology Molecular Function:
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
sequence-specific DNA binding
steroid hormone receptor activity
transcription factor activity, sequence-specific DNA binding
zinc ion binding
Gene Ontology Cellular Component:
nucleoplasm
Keywords:
3D-structure
Alternative splicing
Complete proteome
DNA-binding
Metal-binding
Nucleus
Polymorphism
Receptor
Reference proteome
Transcription
Transcription regulation
Zinc
Zinc-finger

Publication

PubMed ID:
8622695 17974005 10512380 16421571 15489334 24275569 12220494