Names & Taxonomy

Uniprot ID:
Q13117
Entry Name:
DAZ2_HUMAN
Status:
reviewed
Protein Names:
Deleted in azoospermia protein 2
Gene Names:
DAZ2
Gene Names Primary:
DAZ2
Organism:
Homo sapiens (Human)

Structure

Length:
558
Sequence:
MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Cytoplasm

Function

Function:
RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.
Gene Ontology Go:
cytoplasm
nucleus
nucleotide binding
RNA binding
cell differentiation
multicellular organism development
single fertilization
spermatogenesis
Gene Ontology Biological Process:
cell differentiation
multicellular organism development
single fertilization
spermatogenesis
Gene Ontology Molecular Function:
nucleotide binding
RNA binding
Gene Ontology Cellular Component:
cytoplasm
nucleus
Keywords:
Alternative splicing
Complete proteome
Cytoplasm
Developmental protein
Differentiation
Nucleus
RNA-binding
Reference proteome
Repeat
Spermatogenesis

Publication

PubMed ID:
7670487 10936047 12815422 15489334 10857750 11058556 10903443 11390979 12511597 12752250 11095434 11870237 12801575