Names & Taxonomy

Uniprot ID:
Q12926
Entry Name:
ELAV2_HUMAN
Status:
reviewed
Protein Names:
ELAV-like protein 2 (ELAV-like neuronal protein 1) (Hu-antigen B) (HuB) (Nervous system-specific RNA-binding protein Hel-N1)
Gene Names:
ELAVL2 HUB
Gene Names Primary:
ELAVL2
Organism:
Homo sapiens (Human)

Structure

Length:
359
Sequence:
METQLSNGPTCNNTANGPTTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA
Proteomes:
UP000005640

Function

Function:
Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.
Gene Ontology Go:
mRNA 3'-UTR binding
nucleotide binding
poly(A) RNA binding
regulation of transcription, DNA-templated
Gene Ontology Biological Process:
regulation of transcription, DNA-templated
Gene Ontology Molecular Function:
mRNA 3'-UTR binding
nucleotide binding
poly(A) RNA binding
Keywords:
Alternative splicing
Complete proteome
Phosphoprotein
RNA-binding
Reference proteome
Repeat

Publication

PubMed ID:
8158249 7972035 15164053 15489334 17289661 18669648 19413330 20068231