Names & Taxonomy

Uniprot ID:
Q02094
Entry Name:
RHAG_HUMAN
Status:
reviewed
Protein Names:
Ammonium transporter Rh type A (Erythrocyte membrane glycoprotein Rh50) (Erythrocyte plasma membrane 50 kDa glycoprotein) (Rh50A) (Rhesus blood group family type A glycoprotein) (Rh family type A glycoprotein) (Rh type A glycoprotein) (Rhesus blood group-associated ammonia channel) (Rhesus blood group-associated glycoprotein) (CD antigen CD241)
Gene Names:
RHAG RH50
Gene Names Primary:
RHAG
Organism:
Homo sapiens (Human)

Structure

Length:
409
Sequence:
MRFTFPLMAIVLEIAMIVLFGLFVEYETDQTVLEQLNITKPTDMGIFFELYPLFQDVHVMIFVGFGFLMTFLKKYGFSSVGINLLVAALGLQWGTIVQGILQSQGQKFNIGIKNMINADFSAATVLISFGAVLGKTSPTQMLIMTILEIVFFAHNEYLVSEIFKASDIGASMTIHAFGAYFGLAVAGILYRSGLRKGHENEESAYYSDLFAMIGTLFLWMFWPSFNSAIAEPGDKQCRAIVNTYFSLAACVLTAFAFSSLVEHRGKLNMVHIQNATLAGGVAVGTCADMAIHPFGSMIIGSIAGMVSVLGYKFLTPLFTTKLRIHDTCGVHNLHGLPGVVGGLAGIVAVAMGASNTSMAMQAAALGSSIGTAVVGGLMTGLILKLPLWGQPSDQNCYDDSVYWKVPKTR
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Membrane; Multi-pass membrane protein.

Function

Function:
Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.
Gene Ontology Go:
integral component of plasma membrane
plasma membrane
ammonium transmembrane transporter activity
ankyrin binding
ammonium transport
bicarbonate transport
carbon dioxide transport
cellular ion homeostasis
cellular response to nitrogen starvation
erythrocyte development
multicellular organismal iron ion homeostasis
nitrogen utilization
organic cation transport
small molecule metabolic process
transmembrane transport
Gene Ontology Biological Process:
ammonium transport
bicarbonate transport
carbon dioxide transport
cellular ion homeostasis
cellular response to nitrogen starvation
erythrocyte development
multicellular organismal iron ion homeostasis
nitrogen utilization
organic cation transport
small molecule metabolic process
transmembrane transport
Gene Ontology Molecular Function:
ammonium transmembrane transporter activity
ankyrin binding
Gene Ontology Cellular Component:
integral component of plasma membrane
plasma membrane
Keywords:
Alternative splicing
Ammonia transport
Complete proteome
Direct protein sequencing
Disease mutation
Glycoprotein
Membrane
Reference proteome
Transmembrane
Transmembrane helix
Transport

Publication

PubMed ID:
1417776 9442063 14702039 14574404 9473510 3146980 11062476 11861637 14966114 8563755 9454778 9716608 10467273