Names & Taxonomy

Uniprot ID:
P61587
Entry Name:
RND3_HUMAN
Status:
reviewed
Protein Names:
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
Gene Names:
RND3 ARHE RHO8 RHOE
Gene Names Primary:
RND3
Organism:
Homo sapiens (Human)

Structure

Length:
244
Sequence:
MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKSCTVM
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Golgi apparatus membrane; Peripheral membrane protein.

Function

Function:
Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
Gene Ontology Go:
extracellular exosome
focal adhesion
Golgi membrane
GTP binding
GTPase activity
actin cytoskeleton organization
cell adhesion
small GTPase mediated signal transduction
Gene Ontology Biological Process:
actin cytoskeleton organization
cell adhesion
small GTPase mediated signal transduction
Gene Ontology Molecular Function:
GTPase activity
GTP binding
Gene Ontology Cellular Component:
extracellular exosome
focal adhesion
Golgi membrane
Keywords:
3D-structure
Complete proteome
GTP-binding
Golgi apparatus
Lipoprotein
Membrane
Methylation
Nucleotide-binding
Prenylation
Reference proteome
Interacts With:
P31946; P63104

Publication

PubMed ID:
9531558 15489334 8649376 11940653 12163169