Names & Taxonomy
- Uniprot ID:
- P50443
- Entry Name:
- S26A2_HUMAN
- Status:
- reviewed
- Protein Names:
- Sulfate transporter (Diastrophic dysplasia protein) (Solute carrier family 26 member 2)
- Gene Names:
- SLC26A2 DTD DTDST
- Gene Names Primary:
- SLC26A2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 739
- Sequence:
- MSSESKEQHNVSPRDSAEGNDSYPSGIHLELQRESSTDFKQFETNDQCRPYHRILIERQEKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHKTNLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENYNSSIAGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFKSALYKQTVNPILIKVAWKKAAKRKIKEKVVTLGGIQDEMSVQLSHDPLELHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPTVRDSLTNGEYCKKEEENLLFYSVYEAMAFAEVSKNQKGVCVPNGLSLSSD
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane; Multi-pass membrane protein.
Function
- Function:
- Sulfate transporter. May play a role in endochondral bone formation.
- Gene Ontology Go:
- extracellular exosome
integral component of plasma membrane
membrane
plasma membrane
anion:anion antiporter activity
bicarbonate transmembrane transporter activity
chloride channel activity
oxalate transmembrane transporter activity
secondary active sulfate transmembrane transporter activity
sulfate transmembrane transporter activity
3'-phosphoadenosine 5'-phosphosulfate biosynthetic process
3'-phosphoadenosine 5'-phosphosulfate metabolic process
bicarbonate transport
carbohydrate metabolic process
chloride transmembrane transport
glycosaminoglycan metabolic process
ion transport
ossification
oxalate transport
regulation of intracellular pH
regulation of membrane potential
small molecule metabolic process
sulfate transport
transmembrane transport
xenobiotic metabolic process - Gene Ontology Biological Process:
- 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process
3'-phosphoadenosine 5'-phosphosulfate metabolic process
bicarbonate transport
carbohydrate metabolic process
chloride transmembrane transport
glycosaminoglycan metabolic process
ion transport
ossification
oxalate transport
regulation of intracellular pH
regulation of membrane potential
small molecule metabolic process
sulfate transport
transmembrane transport
xenobiotic metabolic process - Gene Ontology Molecular Function:
- anion:anion antiporter activity
bicarbonate transmembrane transporter activity
chloride channel activity
oxalate transmembrane transporter activity
secondary active sulfate transmembrane transporter activity
sulfate transmembrane transporter activity - Gene Ontology Cellular Component:
- extracellular exosome
integral component of plasma membrane
membrane
plasma membrane - Keywords:
- Complete proteome
Disease mutation
Dwarfism
Glycoprotein
Membrane
Phosphoprotein
Polymorphism
Reference proteome
Transmembrane
Transmembrane helix
Transport