Names & Taxonomy
- Uniprot ID:
- P49247
- Entry Name:
- RPIA_HUMAN
- Status:
- reviewed
- Protein Names:
- Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase)
- Gene Names:
- RPIA RPI
- Gene Names Primary:
- RPIA
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 311
- Sequence:
- MQRPGPFSTLYGRVLAPLPGRAGGAASGGGGNSWDLPGSHVRLPGRAQSGTRGGAGNTSTSCGDSNSICPAPSTMSKAEEAKKLAGRAAVENHVRNNQVLGIGSGSTIVHAVQRIAERVKQENLNLVCIPTSFQARQLILQYGLTLSDLDRHPEIDLAIDGADEVDADLNLIKGGGGCLTQEKIVAGYASRFIVIADFRKDSKNLGDQWHKGIPIEVIPMAYVPVSRAVSQKFGGVVELRMAVNKAGPVVTDNGNFILDWKFDRVHKWSEVNTAIKMIPGVVDTGLFINMAERVYFGMQDGSVNMREKPFC
- Proteomes:
- UP000005640
Function
- Pathway:
- Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.
- Catalytic Activity:
- D-ribose 5-phosphate = D-ribulose 5-phosphate.
- Gene Ontology Go:
- cytosol
intracellular membrane-bounded organelle
monosaccharide binding
ribose-5-phosphate isomerase activity
carbohydrate metabolic process
pentose-phosphate shunt
pentose-phosphate shunt, non-oxidative branch
small molecule metabolic process - Gene Ontology Biological Process:
- carbohydrate metabolic process
pentose-phosphate shunt
pentose-phosphate shunt, non-oxidative branch
small molecule metabolic process - Gene Ontology Molecular Function:
- monosaccharide binding
ribose-5-phosphate isomerase activity - Gene Ontology Cellular Component:
- cytosol
intracellular membrane-bounded organelle - Keywords:
- Complete proteome
Disease mutation
Isomerase
Reference proteome - Interacts With:
- Q8N5M1; Q6IPU0; Q75MZ5; Q9H8Y8; P22061; Q06124; Q9H0X6; O75716; Q99757; Q96HA8