Names & Taxonomy
- Uniprot ID:
- P47775
- Entry Name:
- GPR12_HUMAN
- Status:
- reviewed
- Protein Names:
- G-protein coupled receptor 12
- Gene Names:
- GPR12
- Gene Names Primary:
- GPR12
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 334
- Sequence:
- MNEDLKVNLSGLPRDYLDAAAAENISAAVSSRVPAVEPEPELVVNPWDIVLCTSGTLISCENAIVVLIIFHNPSLRAPMFLLIGSLALADLLAGIGLITNFVFAYLLQSEATKLVTIGLIVASFSASVCSLLAITVDRYLSLYYALTYHSERTVTFTYVMLVMLWGTSICLGLLPVMGWNCLRDESTCSVVRPLTKNNAAILSVSFLFMFALMLQLYIQICKIVMRHAHQIALQHHFLATSHYVTTRKGVSTLAIILGTFAACWMPFTLYSLIADYTYPSIYTYATLLPATYNSIINPVIYAFRNQEIQKALCLICCGCIPSSLAQRARSPSDV
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane
Function
- Function:
- Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.
- Gene Ontology Go:
- integral component of plasma membrane
G-protein coupled receptor activity
phosphatidylcholine binding
cellular calcium ion homeostasis
G-protein coupled receptor signaling pathway - Gene Ontology Biological Process:
- cellular calcium ion homeostasis
G-protein coupled receptor signaling pathway - Gene Ontology Molecular Function:
- G-protein coupled receptor activity
phosphatidylcholine binding - Gene Ontology Cellular Component:
- integral component of plasma membrane
- Keywords:
- Cell membrane
Complete proteome
G-protein coupled receptor
Glycoprotein
Lipoprotein
Membrane
Palmitate
Phosphoprotein
Receptor
Reference proteome
Transducer
Transmembrane
Transmembrane helix