Names & Taxonomy
- Uniprot ID:
- P40616
- Entry Name:
- ARL1_HUMAN
- Status:
- reviewed
- Protein Names:
- ADP-ribosylation factor-like protein 1
- Gene Names:
- ARL1
- Gene Names Primary:
- ARL1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 181
- Sequence:
- MGGFFSSIFSSLFGTREMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRKAILVVFANKQDMEQAMTSSEMANSLGLPALKDRKWQIFKTSATKGTGLDEAMEWLVETLKSRQ
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Golgi apparatus membrane
Function
- Function:
- GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus.
- Gene Ontology Go:
- cytoplasm
extracellular exosome
Golgi apparatus
Golgi membrane
trans-Golgi network
enzyme activator activity
GTP binding
GTPase activity
metal ion binding
protein domain specific binding
activation of phospholipase D activity
Golgi organization
Golgi vesicle transport
protein localization to Golgi apparatus
retrograde transport, endosome to Golgi
small GTPase mediated signal transduction
toxin metabolic process - Gene Ontology Biological Process:
- activation of phospholipase D activity
Golgi organization
Golgi vesicle transport
protein localization to Golgi apparatus
retrograde transport, endosome to Golgi
small GTPase mediated signal transduction
toxin metabolic process - Gene Ontology Molecular Function:
- enzyme activator activity
GTPase activity
GTP binding
metal ion binding
protein domain specific binding - Gene Ontology Cellular Component:
- cytoplasm
extracellular exosome
Golgi apparatus
Golgi membrane
trans-Golgi network - Keywords:
- 3D-structure
Alternative splicing
Complete proteome
GTP-binding
Golgi apparatus
Lipoprotein
Magnesium
Membrane
Metal-binding
Myristate
Nucleotide-binding
Reference proteome