Names & Taxonomy
- Uniprot ID:
- P39023
- Entry Name:
- RL3_HUMAN
- Status:
- reviewed
- Protein Names:
- 60S ribosomal protein L3 (HIV-1 TAR RNA-binding protein B) (TARBP-B)
- Gene Names:
- RPL3 OK/SW-cl.32
- Gene Names Orf:
- OK/SW-cl.32
- Gene Names Primary:
- RPL3
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 403
- Sequence:
- MSHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPSKPVHLTAFLGYKAGMTHIVREVDRPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYKNWHKSKKKAFTKYCKKWQDEDGKKQLEKDFSSMKKYCQVIRVIAHTQMRLLPLRQKKAHLMEIQVNGGTVAEKLDWARERLEQQVPVNQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKLPRKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIKNNASTDYDLSDKSINPLGGFVHYGEVTNDFVMLKGCVVGTKKRVLTLRKSLLVQTKRRALEKIDLKFIDTTSKFGHGRFQTMEEKKAFMGPLKKDRIAKEEGA
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Nucleus, nucleolus
Function
- Function:
- The L3 protein is a component of the large subunit of cytoplasmic ribosomes.
- Cross Reference Drug Bank:
- DB04865
- Gene Ontology Go:
- cytoplasm
cytosol
cytosolic large ribosomal subunit
extracellular exosome
focal adhesion
nucleolus
nucleoplasm
nucleus
poly(A) RNA binding
RNA binding
structural constituent of ribosome
cellular nitrogen compound metabolic process
cellular protein metabolic process
cellular response to interleukin-4
gene expression
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
ribosomal large subunit assembly
selenium compound metabolic process
selenocysteine metabolic process
small molecule metabolic process
SRP-dependent cotranslational protein targeting to membrane
translation
translational elongation
translational initiation
translational termination
viral life cycle
viral process
viral transcription - Gene Ontology Biological Process:
- cellular nitrogen compound metabolic process
cellular protein metabolic process
cellular response to interleukin-4
gene expression
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
ribosomal large subunit assembly
selenium compound metabolic process
selenocysteine metabolic process
small molecule metabolic process
SRP-dependent cotranslational protein targeting to membrane
translation
translational elongation
translational initiation
translational termination
viral life cycle
viral process
viral transcription - Gene Ontology Molecular Function:
- poly(A) RNA binding
RNA binding
structural constituent of ribosome - Gene Ontology Cellular Component:
- cytoplasm
cytosol
cytosolic large ribosomal subunit
extracellular exosome
focal adhesion
nucleolus
nucleoplasm
nucleus - Keywords:
- 3D-structure
Acetylation
Complete proteome
Cytoplasm
Direct protein sequencing
Isopeptide bond
Nucleus
Phosphoprotein
Polymorphism
Reference proteome
Ribonucleoprotein
Ribosomal protein
Ubl conjugation