Names & Taxonomy

Uniprot ID:
P39023
Entry Name:
RL3_HUMAN
Status:
reviewed
Protein Names:
60S ribosomal protein L3 (HIV-1 TAR RNA-binding protein B) (TARBP-B)
Gene Names:
RPL3 OK/SW-cl.32
Gene Names Orf:
OK/SW-cl.32
Gene Names Primary:
RPL3
Organism:
Homo sapiens (Human)

Structure

Length:
403
Sequence:
MSHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPSKPVHLTAFLGYKAGMTHIVREVDRPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYKNWHKSKKKAFTKYCKKWQDEDGKKQLEKDFSSMKKYCQVIRVIAHTQMRLLPLRQKKAHLMEIQVNGGTVAEKLDWARERLEQQVPVNQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKLPRKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIKNNASTDYDLSDKSINPLGGFVHYGEVTNDFVMLKGCVVGTKKRVLTLRKSLLVQTKRRALEKIDLKFIDTTSKFGHGRFQTMEEKKAFMGPLKKDRIAKEEGA
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Nucleus, nucleolus

Function

Function:
The L3 protein is a component of the large subunit of cytoplasmic ribosomes.
Cross Reference Drug Bank:
DB04865
Gene Ontology Go:
cytoplasm
cytosol
cytosolic large ribosomal subunit
extracellular exosome
focal adhesion
nucleolus
nucleoplasm
nucleus
poly(A) RNA binding
RNA binding
structural constituent of ribosome
cellular nitrogen compound metabolic process
cellular protein metabolic process
cellular response to interleukin-4
gene expression
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
ribosomal large subunit assembly
selenium compound metabolic process
selenocysteine metabolic process
small molecule metabolic process
SRP-dependent cotranslational protein targeting to membrane
translation
translational elongation
translational initiation
translational termination
viral life cycle
viral process
viral transcription
Gene Ontology Biological Process:
cellular nitrogen compound metabolic process
cellular protein metabolic process
cellular response to interleukin-4
gene expression
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
ribosomal large subunit assembly
selenium compound metabolic process
selenocysteine metabolic process
small molecule metabolic process
SRP-dependent cotranslational protein targeting to membrane
translation
translational elongation
translational initiation
translational termination
viral life cycle
viral process
viral transcription
Gene Ontology Molecular Function:
poly(A) RNA binding
RNA binding
structural constituent of ribosome
Gene Ontology Cellular Component:
cytoplasm
cytosol
cytosolic large ribosomal subunit
extracellular exosome
focal adhesion
nucleolus
nucleoplasm
nucleus
Keywords:
3D-structure
Acetylation
Complete proteome
Cytoplasm
Direct protein sequencing
Isopeptide bond
Nucleus
Phosphoprotein
Polymorphism
Reference proteome
Ribonucleoprotein
Ribosomal protein
Ubl conjugation

Publication

PubMed ID:
15461802 14702039 10591208 15489334 7576925 9582194 12962325 16963496 18669648 19369195 19608861 20068231 21269460 21406692 23349634 24275569 25772364 25944712 23636399 22431104