Names & Taxonomy
- Uniprot ID:
- P31949
- Entry Name:
- S10AB_HUMAN
- Status:
- reviewed
- Protein Names:
- Protein S100-A11 (Calgizzarin) (Metastatic lymph node gene 70 protein) (MLN 70) (Protein S100-C) (S100 calcium-binding protein A11) [Cleaved into: Protein S100-A11, N-terminally processed]
- Gene Names:
- S100A11 MLN70 S100C
- Gene Names Primary:
- S100A11
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 105
- Sequence:
- MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm
Function
- Function:
- Facilitates the differentiation and the cornification of keratinocytes.
- Gene Ontology Go:
- cytoplasm
extracellular exosome
extracellular space
nucleus
ruffle
calcium ion binding
calcium-dependent protein binding
protein homodimerization activity
S100 protein binding
negative regulation of cell proliferation
negative regulation of DNA replication
signal transduction - Gene Ontology Biological Process:
- negative regulation of cell proliferation
negative regulation of DNA replication
signal transduction - Gene Ontology Molecular Function:
- calcium-dependent protein binding
calcium ion binding
protein homodimerization activity
S100 protein binding - Gene Ontology Cellular Component:
- cytoplasm
extracellular exosome
extracellular space
nucleus
ruffle - Keywords:
- 3D-structure
Acetylation
Calcium
Complete proteome
Cytoplasm
Direct protein sequencing
Disulfide bond
Metal-binding
Nucleus
Phosphoprotein
Reference proteome
Repeat - Interacts With:
- P04271