Names & Taxonomy
- Uniprot ID:
- P28332
- Entry Name:
- ADH6_HUMAN
- Status:
- reviewed
- Protein Names:
- Alcohol dehydrogenase 6 (EC 1.1.1.1)
- Gene Names:
- ADH6
- Gene Names Primary:
- ADH6
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 368
- Sequence:
- MCTTGQVIRCKAAILWKPGAPFSIEEVEVAPPKAKEVRIKVVATGLCGTEMKVLGSKHLDLLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSKTQLMSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGAAINTAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATECLNPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGVLPASVQLKISGQLFFSGRSLKGSVFGGWKSRQHIPKLVADYMAEKLNLDPLITHTLNLDKINEAVELMKTGKW
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm.
Function
- Catalytic Activity:
- An alcohol + NAD(+) = an aldehyde or ketone + NADH.
- Cofactor:
- COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
- Cross Reference Drug Bank:
- DB01048 DB00898
- Gene Ontology Go:
- cytosol
extracellular exosome
alcohol dehydrogenase (NAD) activity
zinc ion binding
ethanol oxidation
response to ethanol
small molecule metabolic process
xenobiotic metabolic process - Gene Ontology Biological Process:
- ethanol oxidation
response to ethanol
small molecule metabolic process
xenobiotic metabolic process - Gene Ontology Molecular Function:
- alcohol dehydrogenase (NAD) activity
zinc ion binding - Gene Ontology Cellular Component:
- cytosol
extracellular exosome - Keywords:
- Alternative splicing
Complete proteome
Cytoplasm
Metal-binding
NAD
Oxidoreductase
Phosphoprotein
Polymorphism
Reference proteome
Zinc