Names & Taxonomy
- Uniprot ID:
- P26378
- Entry Name:
- ELAV4_HUMAN
- Status:
- reviewed
- Protein Names:
- ELAV-like protein 4 (Hu-antigen D) (HuD) (Paraneoplastic encephalomyelitis antigen HuD)
- Gene Names:
- ELAVL4 HUD PNEM
- Gene Names Primary:
- ELAVL4
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 380
- Sequence:
- MVMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS
- Proteomes:
- UP000005640
Function
- Function:
- May play a role in neuron-specific RNA processing. Protects CDKN1A mRNA from decay by binding to its 3'-UTR (By similarity). Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF and FOS mRNA.
- Gene Ontology Go:
- AU-rich element binding
mRNA 3'-UTR binding
nucleotide binding
RNA binding
mRNA processing
RNA processing - Gene Ontology Biological Process:
- mRNA processing
RNA processing - Gene Ontology Molecular Function:
- AU-rich element binding
mRNA 3'-UTR binding
nucleotide binding
RNA binding - Keywords:
- 3D-structure
Alternative splicing
Complete proteome
Methylation
Phosphoprotein
Polymorphism
RNA-binding
Reference proteome
Repeat