Names & Taxonomy
- Uniprot ID:
- P24311
- Entry Name:
- COX7B_HUMAN
- Status:
- reviewed
- Protein Names:
- Cytochrome c oxidase subunit 7B, mitochondrial (Cytochrome c oxidase polypeptide VIIb)
- Gene Names:
- COX7B
- Gene Names Primary:
- COX7B
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 80
- Sequence:
- MFPLVKSALNRLQVRSIQQTMARQSHQKRTPDFHDKYGNAVLASGATFCIVTWTYVATQVGIEWNLSPVGRVTPKEWRNQ
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Mitochondrion inner membrane
Function
- Function:
- This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Plays a role in proper central nervous system (CNS) development in vertebrates.
- Cross Reference Drug Bank:
- DB02659
- Gene Ontology Go:
- integral component of membrane
mitochondrial inner membrane
mitochondrial respiratory chain
mitochondrion
respiratory chain complex IV
cytochrome-c oxidase activity
cellular metabolic process
central nervous system development
gene expression
hydrogen ion transmembrane transport
respiratory electron transport chain
small molecule metabolic process
transcription initiation from RNA polymerase II promoter - Gene Ontology Biological Process:
- cellular metabolic process
central nervous system development
gene expression
hydrogen ion transmembrane transport
respiratory electron transport chain
small molecule metabolic process
transcription initiation from RNA polymerase II promoter - Gene Ontology Molecular Function:
- cytochrome-c oxidase activity
- Gene Ontology Cellular Component:
- integral component of membrane
mitochondrial inner membrane
mitochondrial respiratory chain
mitochondrion
respiratory chain complex IV - Keywords:
- Complete proteome
Direct protein sequencing
Membrane
Mitochondrion
Mitochondrion inner membrane
Reference proteome
Transit peptide
Transmembrane
Transmembrane helix