Names & Taxonomy

Uniprot ID:
P24311
Entry Name:
COX7B_HUMAN
Status:
reviewed
Protein Names:
Cytochrome c oxidase subunit 7B, mitochondrial (Cytochrome c oxidase polypeptide VIIb)
Gene Names:
COX7B
Gene Names Primary:
COX7B
Organism:
Homo sapiens (Human)

Structure

Length:
80
Sequence:
MFPLVKSALNRLQVRSIQQTMARQSHQKRTPDFHDKYGNAVLASGATFCIVTWTYVATQVGIEWNLSPVGRVTPKEWRNQ
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Mitochondrion inner membrane

Function

Function:
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Plays a role in proper central nervous system (CNS) development in vertebrates.
Cross Reference Drug Bank:
DB02659
Gene Ontology Go:
integral component of membrane
mitochondrial inner membrane
mitochondrial respiratory chain
mitochondrion
respiratory chain complex IV
cytochrome-c oxidase activity
cellular metabolic process
central nervous system development
gene expression
hydrogen ion transmembrane transport
respiratory electron transport chain
small molecule metabolic process
transcription initiation from RNA polymerase II promoter
Gene Ontology Biological Process:
cellular metabolic process
central nervous system development
gene expression
hydrogen ion transmembrane transport
respiratory electron transport chain
small molecule metabolic process
transcription initiation from RNA polymerase II promoter
Gene Ontology Molecular Function:
cytochrome-c oxidase activity
Gene Ontology Cellular Component:
integral component of membrane
mitochondrial inner membrane
mitochondrial respiratory chain
mitochondrion
respiratory chain complex IV
Keywords:
Complete proteome
Direct protein sequencing
Membrane
Mitochondrion
Mitochondrion inner membrane
Reference proteome
Transit peptide
Transmembrane
Transmembrane helix

Publication

PubMed ID:
8382530 14702039 15772651 15489334 1309697 23122588