Names & Taxonomy
- Uniprot ID:
- P13073
- Entry Name:
- COX41_HUMAN
- Status:
- reviewed
- Protein Names:
- Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1)
- Gene Names:
- COX4I1 COX4
- Gene Names Primary:
- COX4I1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 169
- Sequence:
- MLATRVFSLVGKRAISTSVCVRAHESVVKSEDFSLPAYMDRRDHPLPEVAHVKHLSASQKALKEKEKASWSSLSMDEKVELYRIKFKESFAEMNRGSNEWKTVVGGAMFFIGFTALVIMWQKHYVYGPLPQSFDKEWVAKQTKRMLDMKVNPIQGLASKWDYEKNEWKK
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Mitochondrion inner membrane.
Function
- Function:
- This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
- Cross Reference Drug Bank:
- DB02659
- Gene Ontology Go:
- extracellular exosome
membrane
mitochondrial inner membrane
mitochondrial respiratory chain complex IV
mitochondrion
nucleus
cytochrome-c oxidase activity
aerobic respiration
cellular metabolic process
gene expression
generation of precursor metabolites and energy
hydrogen ion transmembrane transport
mitochondrial electron transport, cytochrome c to oxygen
respiratory electron transport chain
response to nutrient
small molecule metabolic process
transcription initiation from RNA polymerase II promoter - Gene Ontology Biological Process:
- aerobic respiration
cellular metabolic process
gene expression
generation of precursor metabolites and energy
hydrogen ion transmembrane transport
mitochondrial electron transport, cytochrome c to oxygen
respiratory electron transport chain
response to nutrient
small molecule metabolic process
transcription initiation from RNA polymerase II promoter - Gene Ontology Molecular Function:
- cytochrome-c oxidase activity
- Gene Ontology Cellular Component:
- extracellular exosome
membrane
mitochondrial inner membrane
mitochondrial respiratory chain complex IV
mitochondrion
nucleus - Keywords:
- Acetylation
Complete proteome
Direct protein sequencing
Membrane
Mitochondrion
Mitochondrion inner membrane
Phosphoprotein
Polymorphism
Reference proteome
Transit peptide - Interacts With:
- P00395; O00560