Names & Taxonomy

Uniprot ID:
P11836
Entry Name:
CD20_HUMAN
Status:
reviewed
Protein Names:
B-lymphocyte antigen CD20 (B-lymphocyte surface antigen B1) (Bp35) (Leukocyte surface antigen Leu-16) (Membrane-spanning 4-domains subfamily A member 1) (CD antigen CD20)
Gene Names:
MS4A1 CD20
Gene Names Primary:
MS4A1
Organism:
Homo sapiens (Human)

Structure

Length:
297
Sequence:
MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Cell membrane

Function

Function:
This protein may be involved in the regulation of B-cell activation and proliferation.
Cross Reference Drug Bank:
DB00078 DB08935 DB06650 DB00073 DB00081
Gene Ontology Go:
external side of plasma membrane
extracellular exosome
extracellular space
integral component of plasma membrane
MHC class II protein complex binding
B cell proliferation
humoral immune response
Gene Ontology Biological Process:
B cell proliferation
humoral immune response
Gene Ontology Molecular Function:
MHC class II protein complex binding
Gene Ontology Cellular Component:
external side of plasma membrane
extracellular exosome
extracellular space
integral component of plasma membrane
Keywords:
3D-structure
Alternative splicing
B-cell activation
Cell membrane
Complete proteome
Disulfide bond
Lipoprotein
Membrane
Palmitate
Pharmaceutical
Phosphoprotein
Reference proteome
Transmembrane
Transmembrane helix
Interacts With:
Q8N6L0

Publication

PubMed ID:
3260267 2448768 2456210 2466899 14702039 16554811 15489334 16785532 19367720 20038800 22615937 21444918