Names & Taxonomy
- Uniprot ID:
- P11684
- Entry Name:
- UTER_HUMAN
- Status:
- reviewed
- Protein Names:
- Uteroglobin (Clara cell phospholipid-binding protein) (CCPBP) (Clara cells 10 kDa secretory protein) (CC10) (Secretoglobin family 1A member 1) (Urinary protein 1) (UP-1) (UP1) (Urine protein 1)
- Gene Names:
- SCGB1A1 CC10 CCSP UGB
- Gene Names Primary:
- SCGB1A1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 91
- Sequence:
- MKLAVTLTLVTLALCCSSASAEICPSFQRVIETLLMDTPSSYEAAMELFSPDQDMREAGAQLKKLVDTLPQKPRESIIKLMEKIAQSSLCN
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted.
Function
- Function:
- Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.
- Gene Ontology Go:
- extracellular exosome
extracellular space
nuclear envelope
rough endoplasmic reticulum
secretory granule
phospholipase A2 inhibitor activity
polychlorinated biphenyl binding
embryo implantation
female pregnancy
negative regulation of interferon-gamma production
negative regulation of interleukin-13 production
negative regulation of interleukin-4 production
negative regulation of interleukin-5 production
negative regulation of T cell proliferation
negative regulation of transcription from RNA polymerase II promoter
regulation of inflammatory response
regulation of mRNA stability
response to cytokine
response to drug
response to fibroblast growth factor
response to glucocorticoid
response to lipopolysaccharide
response to ozone
response to silicon dioxide
response to xenobiotic stimulus
signal transduction - Gene Ontology Biological Process:
- embryo implantation
female pregnancy
negative regulation of interferon-gamma production
negative regulation of interleukin-13 production
negative regulation of interleukin-4 production
negative regulation of interleukin-5 production
negative regulation of T cell proliferation
negative regulation of transcription from RNA polymerase II promoter
regulation of inflammatory response
regulation of mRNA stability
response to cytokine
response to drug
response to fibroblast growth factor
response to glucocorticoid
response to lipopolysaccharide
response to ozone
response to silicon dioxide
response to xenobiotic stimulus
signal transduction - Gene Ontology Molecular Function:
- phospholipase A2 inhibitor activity
polychlorinated biphenyl binding - Gene Ontology Cellular Component:
- extracellular exosome
extracellular space
nuclear envelope
rough endoplasmic reticulum
secretory granule - Keywords:
- Complete proteome
Direct protein sequencing
Disulfide bond
Phospholipase A2 inhibitor
Polymorphism
Reference proteome
Secreted
Signal - Interacts With:
- P02751; Q13049