Names & Taxonomy
- Uniprot ID:
- P09693
- Entry Name:
- CD3G_HUMAN
- Status:
- reviewed
- Protein Names:
- T-cell surface glycoprotein CD3 gamma chain (T-cell receptor T3 gamma chain) (CD antigen CD3g)
- Gene Names:
- CD3G T3G
- Gene Names Primary:
- CD3G
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 182
- Sequence:
- MEQGKGLAVLILAIILLQGTLAQSIKGNHLVKVYDYQEDGSVLLTCDAEAKNITWFKDGKMIGFLTEDKKKWNLGSNAKDPRGMYQCKGSQNKSKPLQVYYRMCQNCIELNAATISGFLFAEIVSIFVLAVGVYFIAGQDGVRQSRASDKQTLLPNDQLYQPLKDREDDQYSHLQGNQLRRN
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane; Single-pass type I membrane protein.
Function
- Function:
- The CD3 complex mediates signal transduction.
- Cross Reference Drug Bank:
- DB00075
- Gene Ontology Go:
- alpha-beta T cell receptor complex
integral component of plasma membrane
plasma membrane
T cell receptor complex
protein heterodimerization activity
receptor signaling complex scaffold activity
T cell receptor binding
transmembrane signaling receptor activity
cell surface receptor signaling pathway
establishment or maintenance of cell polarity
Fc-gamma receptor signaling pathway involved in phagocytosis
innate immune response
protein complex assembly
protein transport
regulation of immune response
regulation of lymphocyte apoptotic process
T cell activation
T cell costimulation
T cell receptor signaling pathway - Gene Ontology Biological Process:
- cell surface receptor signaling pathway
establishment or maintenance of cell polarity
Fc-gamma receptor signaling pathway involved in phagocytosis
innate immune response
protein complex assembly
protein transport
regulation of immune response
regulation of lymphocyte apoptotic process
T cell activation
T cell costimulation
T cell receptor signaling pathway - Gene Ontology Molecular Function:
- protein heterodimerization activity
receptor signaling complex scaffold activity
T cell receptor binding
transmembrane signaling receptor activity - Gene Ontology Cellular Component:
- alpha-beta T cell receptor complex
integral component of plasma membrane
plasma membrane
T cell receptor complex - Keywords:
- 3D-structure
Complete proteome
Direct protein sequencing
Disulfide bond
Glycoprotein
Immunoglobulin domain
Membrane
Phosphoprotein
Polymorphism
Receptor
Reference proteome
Signal
Transmembrane
Transmembrane helix