Names & Taxonomy

Uniprot ID:
P09466
Entry Name:
PAEP_HUMAN
Status:
reviewed
Protein Names:
Glycodelin (GD) (Placental protein 14) (PP14) (Pregnancy-associated endometrial alpha-2 globulin) (PAEG) (PEG) (Progestagen-associated endometrial protein) (Progesterone-associated endometrial protein)
Gene Names:
PAEP
Gene Names Primary:
PAEP
Organism:
Homo sapiens (Human)

Structure

Length:
180
Sequence:
MLCLLLTLGVALVCGVPAMDIPQTKQDLELPKLAGTWHSMAMATNNISLMATLKAPLRVHITSLLPTPEDNLEIVLHRWENNSCVEKKVLGEKTENPKKFKINYTVANEATLLDTDYDNFLFLCLQDTTTPIQSMMCQYLARVLVEDDEIMQGFIRAFRPLPRHLWYLLDLKQMEEPCRF
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Secreted.

Function

Function:
This protein is, quantitatively, the main protein synthesized and secreted in the endometrium from mid-luteal phase of the menstrual cycle and during the first semester of pregnancy.
Gene Ontology Go:
extracellular region
small molecule binding
apoptotic process
multicellular organism development
positive regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of interleukin-13 secretion
positive regulation of interleukin-6 secretion
transport
Gene Ontology Biological Process:
apoptotic process
multicellular organism development
positive regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of interleukin-13 secretion
positive regulation of interleukin-6 secretion
transport
Gene Ontology Molecular Function:
small molecule binding
Gene Ontology Cellular Component:
extracellular region
Keywords:
3D-structure
Alternative splicing
Complete proteome
Direct protein sequencing
Disulfide bond
Glycoprotein
Polymorphism
Reference proteome
Secreted
Signal
Interacts With:
Q96HH9

Publication

PubMed ID:
3194393 2206398 2006183 17974005 15164053 15489334 3667877 3569148 11278680 7592613 8943270 9239694