Names & Taxonomy
- Uniprot ID:
- P09210
- Entry Name:
- GSTA2_HUMAN
- Status:
- reviewed
- Protein Names:
- Glutathione S-transferase A2 (EC 2.5.1.18) (GST HA subunit 2) (GST class-alpha member 2) (GST-gamma) (GSTA2-2) (GTH2)
- Gene Names:
- GSTA2 GST2
- Gene Names Primary:
- GSTA2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 222
- Sequence:
- MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasm.
Function
- Function:
- Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
- Catalytic Activity:
- RX + glutathione = HX + R-S-glutathione.
- Cross Reference Drug Bank:
- DB00993 DB01008 DB00608 DB00636 DB00903 DB00143 DB00163
- Gene Ontology Go:
- cytosol
extracellular exosome
glutathione transferase activity
epithelial cell differentiation
glutathione derivative biosynthetic process
glutathione metabolic process
small molecule metabolic process
xenobiotic metabolic process - Gene Ontology Biological Process:
- epithelial cell differentiation
glutathione derivative biosynthetic process
glutathione metabolic process
small molecule metabolic process
xenobiotic metabolic process - Gene Ontology Molecular Function:
- glutathione transferase activity
- Gene Ontology Cellular Component:
- cytosol
extracellular exosome - Keywords:
- 3D-structure
Complete proteome
Cytoplasm
Direct protein sequencing
Polymorphism
Reference proteome
Transferase - Interacts With:
- O15217