Names & Taxonomy
- Uniprot ID:
- P08217
- Entry Name:
- CEL2A_HUMAN
- Status:
- reviewed
- Protein Names:
- Chymotrypsin-like elastase family member 2A (EC 3.4.21.71) (Elastase-2A)
- Gene Names:
- CELA2A ELA2A
- Gene Names Primary:
- CELA2A
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 269
- Sequence:
- MIRTLLLSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHKPSVFTRVSNYIDWINSVIANN
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted.
Function
- Function:
- Acts upon elastin.
- Catalytic Activity:
- Preferential cleavage: Leu-|-Xaa, Met-|-Xaa and Phe-|-Xaa. Hydrolyzes elastin.
- Active Site:
- ACT_SITE 73 73 Charge relay system.
- Gene Ontology Go:
- extracellular space
keratohyalin granule
serine hydrolase activity
serine-type endopeptidase activity - Gene Ontology Molecular Function:
- serine hydrolase activity
serine-type endopeptidase activity - Gene Ontology Cellular Component:
- extracellular space
keratohyalin granule - Keywords:
- Complete proteome
Direct protein sequencing
Disulfide bond
Hydrolase
Polymorphism
Protease
Reference proteome
Secreted
Serine protease
Signal
Zymogen