Names & Taxonomy
- Uniprot ID:
- P06126
- Entry Name:
- CD1A_HUMAN
- Status:
- reviewed
- Protein Names:
- T-cell surface glycoprotein CD1a (T-cell surface antigen T6/Leu-6) (hTa1 thymocyte antigen) (CD antigen CD1a)
- Gene Names:
- CD1A
- Gene Names Primary:
- CD1A
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 327
- Sequence:
- MLFLLLPLLAVLPGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDSNSSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSVGFIILAVIVPLLLLIGLALWFRKRCFC
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane
Function
- Function:
- Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
- Cross Reference Drug Bank:
- DB00098
- Gene Ontology Go:
- endosome membrane
integral component of plasma membrane
membrane raft
plasma membrane
beta-2-microglobulin binding
endogenous lipid antigen binding
exogenous lipid antigen binding
lipopeptide binding
adaptive immune response
antigen processing and presentation, exogenous lipid antigen via MHC class Ib
immune response - Gene Ontology Biological Process:
- adaptive immune response
antigen processing and presentation, exogenous lipid antigen via MHC class Ib
immune response - Gene Ontology Molecular Function:
- beta-2-microglobulin binding
endogenous lipid antigen binding
exogenous lipid antigen binding
lipopeptide binding - Gene Ontology Cellular Component:
- endosome membrane
integral component of plasma membrane
membrane raft
plasma membrane - Keywords:
- 3D-structure
Adaptive immunity
Cell membrane
Complete proteome
Disulfide bond
Endosome
Glycoprotein
Immunity
Immunoglobulin domain
Membrane
Polymorphism
Reference proteome
Signal
Transmembrane
Transmembrane helix - Interacts With:
- P61769