Names & Taxonomy
- Uniprot ID:
- P05451
- Entry Name:
- REG1A_HUMAN
- Status:
- reviewed
- Protein Names:
- Lithostathine-1-alpha (Islet cells regeneration factor) (ICRF) (Islet of Langerhans regenerating protein) (REG) (Pancreatic stone protein) (PSP) (Pancreatic thread protein) (PTP) (Regenerating islet-derived protein 1-alpha) (REG-1-alpha) (Regenerating protein I alpha)
- Gene Names:
- REG1A PSPS PSPS1 REG
- Gene Names Primary:
- REG1A
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 166
- Sequence:
- MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVSYKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted.
Function
- Function:
- Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.
- Gene Ontology Go:
- extracellular exosome
carbohydrate binding
growth factor activity
positive regulation of cell proliferation - Gene Ontology Biological Process:
- positive regulation of cell proliferation
- Gene Ontology Molecular Function:
- carbohydrate binding
growth factor activity - Gene Ontology Cellular Component:
- extracellular exosome
- Keywords:
- 3D-structure
Complete proteome
Direct protein sequencing
Disulfide bond
Glycoprotein
Lectin
Pyrrolidone carboxylic acid
Reference proteome
Secreted
Signal