Names & Taxonomy
- Uniprot ID:
- P01859
- Entry Name:
- IGHG2_HUMAN
- Status:
- reviewed
- Protein Names:
- Ig gamma-2 chain C region
- Gene Names:
- IGHG2
- Gene Names Primary:
- IGHG2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 326
- Sequence:
- ASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTYTCNVDHKPSNTKVDKTVERKCCVECPPCPAPPVAGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTFRVVSVLTVVHQDWLNGKEYKCKVSNKGLPAPIEKTISKTKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDISVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted.
Function
- Gene Ontology Go:
- blood microparticle
external side of plasma membrane
extracellular exosome
extracellular region
extracellular space
immunoglobulin complex, circulating
antigen binding
immunoglobulin receptor binding
B cell receptor signaling pathway
complement activation
complement activation, classical pathway
defense response to bacterium
Fc-gamma receptor signaling pathway involved in phagocytosis
innate immune response
phagocytosis, engulfment
phagocytosis, recognition
positive regulation of B cell activation - Gene Ontology Biological Process:
- B cell receptor signaling pathway
complement activation
complement activation, classical pathway
defense response to bacterium
Fc-gamma receptor signaling pathway involved in phagocytosis
innate immune response
phagocytosis, engulfment
phagocytosis, recognition
positive regulation of B cell activation - Gene Ontology Molecular Function:
- antigen binding
immunoglobulin receptor binding - Gene Ontology Cellular Component:
- blood microparticle
external side of plasma membrane
extracellular exosome
extracellular region
extracellular space
immunoglobulin complex, circulating - Keywords:
- 3D-structure
Complete proteome
Direct protein sequencing
Disulfide bond
Glycoprotein
Immunoglobulin C region
Immunoglobulin domain
Reference proteome
Secreted - Interacts With:
- Q28109